Hydroxypropyl-β-cyclodextrin
Hydroxypropyl-β-cyclodextrin structure
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Common Name | Hydroxypropyl-β-cyclodextrin | ||
|---|---|---|---|---|
| CAS Number | 128446-35-5 | Molecular Weight | 1541.538 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 1521.9±60.0 °C at 760 mmHg | |
| Molecular Formula | C63H112O42 | Melting Point | 278ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | 874.2±32.9 °C | |
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SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.
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Arachidonic acid impairs hypothalamic leptin signaling and hepatic energy homeostasis in mice.
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J. Neurosci. 34(46) , 15306-18, (2014) The paraventricular nucleus of the hypothalamus (PVH) contains a heterogeneous cluster of Sim1-expressing cell types that comprise a major autonomic output nucleus and play critical roles in the control of food intake and energy homeostasis. The roles of spec... |
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Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease.
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Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation.
Respir. Res. 16 , 77, (2015) Potential involvement of the CCR10/CCL28 axis was recently reported in murine models of allergic asthma. If confirmed, blockade of the CCR10 receptor would represent an alternative to current asthma therapies. We evaluated the effect of a novel Protein Epitop... |
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Peroral amphotericin B polymer nanoparticles lead to comparable or superior in vivo antifungal activity to that of intravenous Ambisome® or Fungizone™.
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When administered to rats in a cold environment, 3,4-methylenedioxymethamphetamine reduces brown adipose tissue thermogenesis and increases tail blood flow: Effects of pretreatment with 5-HT1A and dopamine D2 antagonists
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Synthesis, cytotoxicity, and phase-solubility study of cyclodextrin click clusters.
J. Pharm. Sci. 103(10) , 3183-9, (2014) To explore the possibility of cyclodextrin click clusters (CCCs) as a new cyclodextrin-based excipient, we prepared three different CCCs; heptakis{6-(4-hydroxymethyl-1H-[1,2,3]triazol-1-yl)-6-deoxy}-β-cyclodextrin (HT-β-CD), heptakis{6-(4-hydroxymethyl-1H-[1,... |