Psilocin

Psilocin Structure
Psilocin structure
Common Name Psilocin
CAS Number 520-53-6 Molecular Weight 204.268
Density 1.2±0.1 g/cm3 Boiling Point 392.8±32.0 °C at 760 mmHg
Molecular Formula C12H16N2O Melting Point 173-176°
MSDS Chinese USA Flash Point 191.3±25.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Analysis of psilocin, bufotenine and LSD in hair.

J. Anal. Toxicol. 39(2) , 126-9, (2015)

A method for the simultaneous extraction of the hallucinogens psilocin, bufotenine, lysergic acid diethylamide (LSD) as well as iso-LSD, nor-LSD and O-H-LSD from hair with hydrochloride acid and methanol is presented. Clean-up of the hair extracts is performe...

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

Drug Metab. Dispos. 38(3) , 386-95, (2010)

We have examined the glucuronidation of psilocin, a hallucinogenic indole alkaloid, by the 19 recombinant human UDP-glucuronosyltransferases (UGTs) of subfamilies 1A, 2A, and 2B. The glucuronidation of 4-hydroxyindole, a related indole that lacks the N,N-dime...

Enzyme-assisted synthesis of the glucuronide conjugate of psilocin, an hallucinogenic component of magic mushrooms.

Drug Test. Anal. 3(9) , 594-6, (2011)

An enzyme-assisted synthesis of psilocin glucuronide (PCG), a metabolite excreted in the urine of magic mushroom (MM) users, is described. In the presence of Aroclor 1254 pretreated rat liver microsomes, psilocin and the cofactor UDPGA were incubated for 20 h...

The Meixner test in the detection of alpha-amanitin and false-positive reactions caused by psilocin and 5-substituted tryptamines.

Ann. Emerg. Med. 44(2) , 114-20, (2004)

The Meixner test has been suggested to identify the presence of alpha-amanitin, one of the toxic compounds in Amanita mushrooms. We attempted to determine the detection limit of the Meixner test for alpha-amanitin and to determine the percentage of positive s...

Fungal hallucinogens psilocin, ibotenic acid, and muscimol: analytical methods and biologic activities.

Ther. Drug Monit. 35(4) , 420-42, (2013)

Psychoactive drugs of fungal origin, psilocin, ibotenic acid, and muscimol among them have been proposed for recreational use and popularized since the 1960s, XX century. Despite their well-documented neurotoxicity, they reached reputation of being safe and n...

Comparative study of ATR and transflection IR spectroscopic techniques for the analysis of hallucinogenic mushrooms.

Forensic Sci. Int. 195(1-3) , 36-41, (2010)

This paper compares the use of ATR and transflection spectroscopic techniques for the qualitative analysis of psilocin extracted from hallucinogenic mushrooms and control spiked mushrooms. Both techniques gave comparable results and agreed with prior GC/MS an...

Turn on, tune in, but don't drop out: The impact of neo-liberalism on magic mushroom users' (in)ability to imagine collectivist social worlds.

Int. J. Drug Policy 21(6) , 445-51, (2010)

Between 2002 and 2005 fresh or unprepared psilocin-based 'magic' mushrooms were legal to possess and traffic in the UK, and commercial sales demonstrated a significant market for this hallucinogenic drug. During and after this time there has been relatively l...

Development of a psilocin immunoassay for serum and blood samples.

Int. J. Legal Med. 118(6) , 326-31, (2004)

After the immunisation of rabbits with a psilocin-specific immunogen, polyclonal antisera were obtained. With these antisera a competitive, heterogeneous radioimmunoassay for the detection of psilocin was developed. As tracer a derivative of psilocin was synt...

Investigation into the temporal stability of aqueous standard solutions of psilocin and psilocybin using high performance liquid chromatography.

Sci. Justice 46(2) , 91-6, (2006)

This paper reports an investigation into the temporal stability of aqueous solutions of psilocin and psilocybin reference drug standards over a period of fourteen days. This study was performed using high performance liquid chromatography utilising a (95:5% v...

The determination of psilocin and psilocybin in hallucinogenic mushrooms by HPLC utilizing a dual reagent acidic potassium permanganate and tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence detection system.

J. Forensic Sci. 51(1) , 45-51, (2006)

This paper describes a procedure for the determination of psilocin and psilocybin in mushroom extracts using high-performance liquid chromatography with postcolumn chemiluminescence detection. A number of extraction methods for psilocin and psilocybin in hall...