5-(4’-Hydroxyphenyl)-5-ethylhydantion

5-(4’-Hydroxyphenyl)-5-ethylhydantion Structure
5-(4’-Hydroxyphenyl)-5-ethylhydantion structure
Common Name 5-(4’-Hydroxyphenyl)-5-ethylhydantion
CAS Number 61837-66-9 Molecular Weight 220.22500
Density 1.277g/cm3 Boiling Point N/A
Molecular Formula C11H12N2O3 Melting Point 260ºC
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Stereoselective metabolism and pharmacogenetic control of 5-phenyl-5-ethylhydantoin (nirvanol) in humans.

J. Pharmacol. Exp. Ther. 230(1) , 28-33, (1984)

Aromatic hydroxylation of 5-phenyl-5-ethylhydantoin (PEH) has been investigated in humans. Single oral doses of S-PEH (247 mumol) were given to seven extensive and seven poor hydroxylators of mephenytoin. Urinary recovery of PEH and 5-(4-hydroxyphenyl)-5-ethy...

Identification of mephenytoin metabolites in the dog.

Drug Metab. Dispos. 8 , 173, (1980)

In two dogs p-hydroxymephenytoin, m-hydroxymephenytoin, 5-ethyl-5-phenylhydantoin (nirvanol), and 5-ethyl-5-(p-hydroxyphenyl)hydantoin (p-hydroxynirvanol) were identified by use of synthetic metabolites as standards for comparison.