2-Piperazinecarboxylic acid dihydrochloride

2-Piperazinecarboxylic acid dihydrochloride Structure
2-Piperazinecarboxylic acid dihydrochloride structure
Common Name 2-Piperazinecarboxylic acid dihydrochloride
CAS Number 3022-15-9 Molecular Weight 203.067
Density N/A Boiling Point 313.6ºC at 760 mmHg
Molecular Formula C5H12Cl2N2O2 Melting Point 266-269ºC
MSDS Chinese USA Flash Point 143.5ºC
Symbol GHS07
GHS07
Signal Word Warning

Heterocyclic amine-modified polyethylenimine as gene carriers for transfection of mammalian cells.

Eur. J. Pharm. Biopharm. 96 , 76-88, (2015)

Branched polyethylenimine (PEI) is extensively used as a polycationic non-viral vector for gene delivery. Polyplexes formed with PEI are believed to be released from endocytotic vesicles by the osmotic burst mechanism in the rate-limiting step in transfection...

Gene delivery efficiency and cytotoxicity of heterocyclic amine-modified PAMAM and PPI dendrimers.

Mater. Sci. Eng. C. Mater. Biol. Appl. 61 , 791-800, (2016)

Poly-(amidoamine) (PAMAM) and poly-(propylenimine) (PPI) are the two most widely investigated dendrimers for drug and gene delivery. In order to enhance DNA transfection activity of these dendrimers, generation 3 and 4 PAMAM and generation 4 and 5 PPI were mo...