3,4-methylenedioxymethamphetamine

3,4-methylenedioxymethamphetamine Structure
3,4-methylenedioxymethamphetamine structure
Common Name 3,4-methylenedioxymethamphetamine
CAS Number 42542-10-9 Molecular Weight 193.24200
Density 1.1 g/cm3 Boiling Point 318ºC at 760 mmHg
Molecular Formula C11H15NO2 Melting Point N/A
MSDS N/A Flash Point 9℃
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

Measuring effects of MDMA (ecstasy) abuse on the rate of cerebral serotonin synthesis.

J. Neurochem. 131(5) , 541-5, (2014)

Brain serotonin synthesis in MDMA (ecstasy) polydrug users: an alpha-[(11) C]methyl-l-tryptophan study.

J. Neurochem. 131(5) , 634-44, (2014)

3,4-Methylenedioxymethamphetamine (MDMA, ecstasy) use may have long-term neurotoxic effects. In this study, positron emission tomography with the tracer alpha-[(11) C]methyl-l-tryptophan ((11) C-AMT) was used to compare human brain serotonin (5-HT) synthesis ...

3,4-Methylenedioxy-methamphetamine induces in vivo regional up-regulation of central nicotinic receptors in rats and potentiates the regulatory effects of nicotine on these receptors.

Neurotoxicology 35 , 41-9, (2013)

Nicotine (NIC), the main psychostimulant compound of smoked tobacco, exerts its effects through activation of central nicotinic acetylcholine receptors (nAChR), which become up-regulated after chronic administration. Recent work has demonstrated that the recr...

Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner.

J. Psychoactive Drugs 44(5) , 410-7, (2012)

Psychedelic drugs have long been known to be capable of inducing mystical or transcendental experiences. However, given the common "recreational" nature of much present-day psychedelic use, with typical doses tending to be lower than those commonly taken in t...

A case of drug-facilitated sexual assault involving 3,4-methylenedioxy-methylamphetamine.

J. Psychoactive Drugs 45(1) , 94-7, (2013)

Typical scenarios of drug-facilitated sexual assaults usually involve victims having ingested a drink after which they had little, partial or no recollection of events for a period of time. We were surprised by the case of a woman who was sexually assaulted a...

Stability of 3,4-methylenedioxymethampetamine (MDMA), 4-methylmethcathinone (mephedrone) and 3-trifluromethylphenylpiperazine (3-TFMPP) in formalin solution.

J. Anal. Toxicol. 37(7) , 440-6, (2013)

Occasionally, the only postmortem samples available for analysis are contaminated with formaldehyde, either due to embalming prior to sampling or because analysis is carried out only when formalin-fixed tissues retained for histological study are available. F...

Dental health of Irish alcohol/drug abuse treatment centre residents.

Community Dent. Health 29(4) , 263-7, (2012)

This study examines the independent and combined impact of 'alcohol only' and 'alcohol plus drug' abuse on the dental health of Irish alcohol/drug abuse treatment centre residents, comparing their dental caries experience.Four Irish treatment centres were vis...

Effect of repeated exposure to MDMA on the function of the 5-HT transporter as assessed by synaptosomal 5-HT uptake.

Brain Res. Bull. 91 , 52-7, (2013)

Recent studies have demonstrated that a preconditioning regimen (i.e., repeated low doses) of MDMA provides protection against the reductions in tissue concentrations of 5-HT and 5-HT transporter (SERT) density and/or expression produced by a subsequent binge...

Ecstasy (3, 4-methylenedioxymethamphetamine) use among Japanese rave population.

Psychiatry Clin. Neurosci. 67(1) , 12-9, (2013)

The aim of this study was to examine the prevalence of 3, 4-methylenedioxymethamphetamine (MDMA) use and to identify characteristics of MDMA users among rave attendees in Japan. This is the first rave-population study focusing on MDMA use in Japan.The anonymo...

The varieties of ecstasy experience: a phenomenological ethnography.

J. Psychoactive Drugs 45(4) , 347-54, (2013)

Ecstasy (MDMA) has attracted widespread attention with its association as a "recreational substance" that is concentrated in club and rave settings. This paper outlines a phenomenologically grounded ethnographic study of the experiences of ecstasy users in th...