SU 5614

SU 5614 Structure
SU 5614 structure
Common Name SU 5614
CAS Number 1055412-47-9 Molecular Weight 272.73000
Density N/A Boiling Point N/A
Molecular Formula C15H13ClN2O Melting Point N/A
MSDS USA Flash Point N/A

Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia.

Oncotarget 6 , 38804-15, (2015)

Internal tandem duplications within the juxtamembrane region of the FMS-like tyrosine kinase receptor FLT3 (FLT3-ITD) represents one of the most common mutations in patients with acute myeloid leukemia (AML) which results in constitutive aberrant activation, ...

VEGF-A/NRP1 stimulates GIPC1 and Syx complex formation to promote RhoA activation and proliferation in skin cancer cells.

Biol. Open 4 , 1063-76, (2015)

Neuropilin-1 (NRP1) has been identified as a VEGF-A receptor. DJM-1, a human skin cancer cell line, expresses endogenous VEGF-A and NRP1. In the present study, the RNA interference of VEGF-A or NRP1 suppressed DJM-1 cell proliferation. Furthermore, the overex...