Hyoscyamine

Hyoscyamine Structure
Hyoscyamine structure
Common Name Hyoscyamine
CAS Number 101-31-5 Molecular Weight 289.369
Density 1.2±0.1 g/cm3 Boiling Point 429.8±45.0 °C at 760 mmHg
Molecular Formula C17H23NO3 Melting Point 108.5ºC
MSDS N/A Flash Point 213.7±28.7 °C

Role of 17-beta estradiol in baroreflex sensitivity in the nucleus tractus solitarii via the autonomic system in ovariectomized rats.

Neurosciences (Riyadh.) 18(2) , 126-32, (2013)

To investigate the effect of estrogen exerted through the autonomic system in the nucleus tractus solitarii (NTS) on increasing the sensitivity of the baroreflex under conditions of acute hypertension in ovariectomized rats.In this experimental study, conduct...

Comparison of subcellular distribution and functions between exogenous and endogenous M1 muscarinic acetylcholine receptors.

Life Sci. 93(1) , 17-23, (2013)

Recombinant systems have been used for evaluating the properties of G-protein-coupled receptors (GPCRs) on the assumption of cell surface expression. However, many GPCRs, including muscarinic acetylcholine receptors (mAChRs), have also been reported to be dis...

Sudden unexpected death in a mouse model of Dravet syndrome.

J. Clin. Invest. 123(4) , 1798-808, (2013)

Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in intractable epilepsies, but physiological mechanisms that lead to SUDEP are unknown. Dravet syndrome (DS) is an infantile-onset intractable epilepsy caused by heterozygous loss-o...

[Severe and uncommon complications of anticholinesterase intoxication in children].

Harefuah 152(7) , 391-4, 434, (2013)

The Northern region of the Negev desert is an endemic area of organophosphate and carbamate intoxications in Bedouin children. Most victims are intoxicated by drinking the poisonous material kept by the parents in soft drink bottles. Signs and symptoms of int...

[Neuro-autonomic inhibition and haemodynamics management optimization during cesarean section under spinal anaesthesia in pregnant women with gestosis].

Anesteziol. Reanimatol. (6) , 48-51, (2012)

Results showed that autonomic nervous system (ANS) and blood circulation system (BCS) dysfunction in 3rd trimester pregnant women with gestosis are more pronounced, than in healthy pregnant women, despite the prescribed treatment. The most significant disturb...

Equine piroplasmosis treatment protocols: specific effect on orocaecal transit time as measured by the lactose 13C-ureide breath test.

Equine Vet. J. Suppl. (43) , 62-7, (2012)

Imidocarb dipropionate is the drug of choice for equine piroplasmosis but its administration causes severe colic and diarrhoea. An imidocarb protocol that reduces these effects is needed.1) Quantification of the effects of imidocarb dipropionate on equine oro...

[Scopolamine and hyoscyamine synthesis in hair roots culture of Datura metel].

Zhongguo Zhong Yao Za Zhi 37(21) , 3223-8, (2012)

To establish the hair roots culture system of Datura metel and study the hair roots growth and biosynthesis of scopolamine and hyoscyamine in hair roots culturing system.Direct degermed cotyledon of wild D. metel was infected by Agrobacterium tumefaciens stra...

M-cholinoreactivity of erythrocytes of non-pregnant and pregnant women evaluated by changes in the rate of erythrocyte agglutination under the influence of acetylcholine.

Bull. Exp. Biol. Med. 154(2) , 180-3, (2012)

Acetylcholine (5.5×10(-10)-5.5×10(-6)M) accelerated erythrocyte agglutination in men, non-pregnant women in follicular phase of the menstrual cycle, and pregnant women in the first trimester. The effect was blocked with atropine (5.5×10(-6)M). Acetylcholine h...

Question 2: can a conservative approach to the treatment of hypertrophic pyloric stenosis with atropine be considered a real alternative to surgical pyloromyotomy?

Arch. Dis. Child. 98(6) , 474-7, (2013)

Atropine for critical care intubation in a cohort of 264 children and reduced mortality unrelated to effects on bradycardia.

PLoS ONE 8(2) , e57478, (2013)

Atropine has is currently recommended to facilitate haemodynamic stability during critical care intubation. Our objective was to determine whether atropine use at induction influences ICU mortality.A 2-year prospective, observational study of all first non-pl...