(R)-(-)-Epichlorohydrin

(R)-(-)-Epichlorohydrin Structure
(R)-(-)-Epichlorohydrin structure
Common Name (R)-(-)-Epichlorohydrin
CAS Number 51594-55-9 Molecular Weight 92.524
Density 1.2±0.1 g/cm3 Boiling Point 116.1±0.0 °C at 760 mmHg
Molecular Formula C3H5ClO Melting Point -48ºC
MSDS Chinese Flash Point 33.9±0.0 °C
Symbol GHS02 GHS05 GHS06 GHS08
GHS02, GHS05, GHS06, GHS08
Signal Word Danger

Halogenated derivatives QSAR model using spectral moments to predict haloacetic acids (HAA) mutagenicity.

Bioorg. Med. Chem. 16 , 5720-32, (2008)

The risk of the presence of haloacetic acids in drinking water as chlorination by-products and the shortage of experimental mutagenicity data for most of them requires a research work. This paper describes a QSAR model to predict direct mutagenicity for these...

The intramolecular asymmetric Pauson-Khand cyclization as a novel and general stereoselective route to benzindene prostacyclins: synthesis of UT-15 (treprostinil).

J. Org. Chem. 69 , 1890, (2004)

A general and novel solution to the synthesis of biologically important stable analogues of prostacyclin PGI(2), namely benzindene prostacyclins, has been achieved via the stereoselective intramolecular Pauson-Khand cyclization (PKC). This work illustrates fo...

Strategy for the enantioselective synthesis of trans-2,4-disubstituted piperidines: application to the CCR3 antagonist IS811.

J. Org. Chem. 71 , 8975, (2006)

A strategy for the enantioselective synthesis of trans-2,4-disubstituted piperidines is proposed and applied to the preparation of IS811, a potent CCR3 antagonist. The C2 stereocenter is derived from commercial (R)-epichlorohydrin, while the C4 stereocenter i...

Synlett , 2151, (2006)