2-Acetoxy-N,N,N-trimethylethanaminium perchlorate
2-Acetoxy-N,N,N-trimethylethanaminium perchlorate structure
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Common Name | 2-Acetoxy-N,N,N-trimethylethanaminium perchlorate | ||
|---|---|---|---|---|
| CAS Number | 927-86-6 | Molecular Weight | 245.658 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H16ClNO6 | Melting Point | 115 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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VPAC1 receptors regulate intestinal secretion and muscle contractility by activating cholinergic neurons in guinea pig jejunum.
Am. J. Physiol. Gastrointest. Liver Physiol. 306(9) , G748-58, (2014) In the gastrointestinal tract, vasoactive intestinal peptide (VIP) is found exclusively within neurons. VIP regulates intestinal motility via neurally mediated and direct actions on smooth muscle and secretion by a direct mucosal action, and via actions on su... |
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Genetic dissection of the vav2-rac1 signaling axis in vascular smooth muscle cells.
Mol. Cell. Biol. 34(24) , 4404-19, (2014) Vascular smooth muscle cells (vSMCs) are key in the regulation of blood pressure and the engagement of vascular pathologies, such as hypertension, arterial remodeling, and neointima formation. The role of the Rac1 GTPase in these cells remains poorly characte... |
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Tocotrienol Rich Palm Oil Extract Is More Effective Than Pure Tocotrienols at Improving Endothelium-Dependent Relaxation in the Presence of Oxidative Stress.
Oxid. Med. Cell. Longev. 2015 , 150829, (2015) Oxidative endothelial dysfunction is a critical initiator of vascular disease. Vitamin E is an effective antioxidant but attempts to use it to treat vascular disorders have been disappointing. This study investigated whether tocotrienols, the less abundant co... |
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Muscarinic M₃ receptors contribute to allergen-induced airway remodeling in mice.
Am. J. Respir. Cell. Mol. Biol. 50(4) , 690-8, (2014) Asthma is a chronic obstructive airway disease, characterized by inflammation and remodeling. Acetylcholine contributes to symptoms by inducing bronchoconstriction via the muscarinic M3 receptor. Recent evidence suggests that bronchoconstriction can regulate ... |
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Decreased Kv1.5 expression in intrauterine growth retardation rats with exaggerated pulmonary hypertension.
Am. J. Physiol. Lung Cell. Mol. Physiol. 305(11) , L856-65, (2013) Chronic hypoxia pulmonary hypertension (CH-PHT) in adulthood is likely to be of fetal origin following intrauterine growth retardation (IUGR). Oxygen (O₂)-sensitive voltage-gated potassium channels (Kv channels) in resistance pulmonary artery smooth muscle ce... |
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Decrease in neuronal nicotinic acetylcholine receptor subunit and PSD-93 transcript levels in the male mouse MPG after cavernous nerve injury or explant culture.
Am. J. Physiol. Renal Physiol. 305(10) , F1504-12, (2013) Quantitative real-time PCR was used to test whether cavernous nerve injury leads to a decrease in major pelvic ganglia (MPG) neuronal nicotinic ACh receptor (nAChR) subunit and postsynaptic density (PSD)-93 transcript levels. Subunits α3, β4, and α7, commonly... |
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Acetylcholine controls GABA-, glutamate-, and glycine-dependent giant depolarizing potentials that govern spontaneous motoneuron activity at the onset of synaptogenesis in the mouse embryonic spinal cord.
J. Neurosci. 34(18) , 6389-404, (2014) A remarkable feature of early neuronal networks is their endogenous ability to generate spontaneous rhythmic electrical activity independently of any external stimuli. In the mouse embryonic SC, this activity starts at an embryonic age of ∼ 12 d and is charac... |
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Role of nitric oxide synthase isoforms for ophthalmic artery reactivity in mice.
Exp. Eye Res. 127 , 1-8, (2014) Nitric oxide synthases (NOS) are involved in regulation of ocular vascular tone and blood flow. While endothelial NOS (eNOS) has recently been shown to mediate endothelium-dependent vasodilation in mouse retinal arterioles, the contribution of individual NOS ... |
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Vascular structure and function in the medial collateral ligament of anterior cruciate ligament transected rabbit knees.
J. Orthop. Res. 32(9) , 1104-10, (2014) To determine if decreased vascular responsiveness in the medial collateral ligament (MCL) of anterior cruciate ligament transected (ACL-t) rabbit knees is due to pericyte deficiency associated with angiogenesis. Vascular responses to potassium chloride (KCl),... |
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Endothelial nitric oxide synthase uncoupling and microvascular dysfunction in the mesentery of mice deficient in α-galactosidase A.
Am. J. Physiol. Gastrointest. Liver Physiol. 306(2) , G140-6, (2014) A defect in the gene for the lysosomal enzyme α-galactosidase A (Gla) results in globotriaosylceramide (Gb3) accumulation in Fabry disease and leads to premature death from cardiac and cerebrovascular events. However, gastrointestinal symptoms are often first... |