oxycodone
oxycodone structure
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Common Name | oxycodone | ||
|---|---|---|---|---|
| CAS Number | 76-42-6 | Molecular Weight | 315.364 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 501.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C18H21NO4 | Melting Point | 218-220° | |
| MSDS | N/A | Flash Point | 257.1±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans.
J. Pharmacol. Exp. Ther. 351(2) , 259-69, (2014) The transient receptor potential (subfamily M, member 8; TRPM8) is a nonselective cation channel localized in primary sensory neurons, and is a candidate for cold thermosensing, mediation of cold pain, and bladder overactivity. Studies with TRPM8 knockout mic... |
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Spontaneous resolution of quadrilateral space syndrome: a case report.
Am. J. Phys. Med. Rehabil. 94(1) , e1-5, (2015) A case of quadrilateral space syndrome is presented, where a large near-circumferential glenoid labrum tear led to a paralabral cyst that dissected into the quadrilateral space and caused a compressive neuropathy of the axillary nerve. This led to a 6-mo hist... |
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Rational prescribing.
Minn. Med. 96(3) , 4, (2013)
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Extended-release oxycodone and acetaminophen (Xartemis XR).
Med. Lett. Drugs Ther. 56(1447) , 59-60, (2014)
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Opioid prescribing patterns after Mohs micrographic surgery and standard excision: a survey of American Society for Dermatologic Surgery members and a chart review at a single institution.
Dermatol. Surg. 40(8) , 906-11, (2014) Little is known about postoperative opioid prescribing patterns among dermatologic surgeons.To better understand postoperative opioid prescribing patterns among dermatologic surgeons in the United States.Two-part analysis consisting of a retrospective chart r... |
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Pre-emptive analgesia with pregabalin and celecoxib decreases postsurgical pain following maxillomandibular advancement surgery: a randomized controlled clinical trial.
J. Oral Maxillofac. Surg. 72(10) , 1909-14, (2014) The purpose of this study was to determine the efficacy of pre-emptive analgesia with pregabalin and celecoxib on narcotic consumption and perceived pain in adult patients undergoing maxillomandibular advancement surgery for obstructive sleep apnea.This was a... |
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Trends in opioid analgesic abuse and mortality in the United States.
N. Engl. J. Med. 372(3) , 241-8, (2015) The use of prescription opioid medications has increased greatly in the United States during the past two decades; in 2010, there were 16,651 opioid-related deaths. In response, hundreds of federal, state, and local interventions have been implemented. We des... |
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Opioid overdose mortality in Kansas, 2001-2011: toxicologic evaluation of intent.
J. Anal. Toxicol. 37(9) , 629-35, (2013) Drug concentration is a factor in the determination of the manner of death, but considerable overlap exists between therapeutic and toxic concentrations. This study aims to quantify opioid mortality in Kansas from use of fentanyl, methadone and oxycodone and ... |
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Determinants of increased opioid-related mortality in the United States and Canada, 1990-2013: a systematic review.
Am. J. Public Health 104(8) , e32-42, (2014) We review evidence of determinants contributing to increased opioid-related mortality in the United States and Canada between 1990 and 2013. We identified 17 determinants of opioid-related mortality and mortality increases that we classified into 3 categories... |
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Single periarticular local infiltration analgesia reduces opiate consumption until 48 hours after total knee arthroplasty. A randomized placebo-controlled trial involving 56 patients.
Acta Orthop. 85(6) , 614-9, (2014) Randomized trials evaluating efficacy of local infiltration analgesia (LIA) have been published but many of these lack standardized analgesics. There is a paucity of reports on the effects of LIA on functional capability and quality of life.56 patients underg... |