![]() Tetrahydrozoline hydrochloride structure
|
Common Name | Tetrahydrozoline hydrochloride | ||
---|---|---|---|---|
CAS Number | 522-48-5 | Molecular Weight | 236.740 | |
Density | N/A | Boiling Point | 393.5ºC at 760 mmHg | |
Molecular Formula | C13H17ClN2 | Melting Point | 197 °C | |
MSDS | Chinese USA | Flash Point | 191.8ºC | |
Symbol |
![]() GHS07 |
Signal Word | Warning |
Method development for impurity profiling in SFC: The selection of a dissimilar set of stationary phases.
J. Pharm. Biomed. Anal. 111 , 333-43, (2015) Supercritical fluid chromatography (SFC) is drawing considerable interest as separation technique in the pharmaceutical industry. The technique is already well established in chiral separations both analytically and on a preparative scale. The use of SFC as a... |
|
A comparative kinetic and mechanistic study between tetrahydrozoline and naphazoline toward photogenerated reactive oxygen species.
Photochem. Photobiol. 86(1) , 23-30, (2010) Kinetic and mechanistic aspects of the vitamin B2 (riboflavin [Rf])-sensitized photo-oxidation of the imidazoline derivates (IDs) naphazoline (NPZ) and tetrahydrozoline (THZ) were investigated in aqueous solution. The process appears as important on biomedica... |
|
[Nasal decongestants and eye drops: keep out of children's reach!].
Perspect. Infirm. 10(2) , 63, (2013)
|
|
A randomized controlled trial of intralesional bevacizumab injection on primary pterygium: preliminary results.
Cornea 30(11) , 1213-8, (2011) To evaluate the efficacy and safety of intralesional injection of bevacizumab on primary pterygium treatment.In this randomized controlled trial, each primary pterygium patient was randomized to receive either an intralesional injection of bevacizumab 2 mg (1... |
|
Simple HPLC determination of benzalkonium chloride in ophthalmic formulations containing antazoline and tetrahydrozoline.
PDA J. Pharm. Sci. Technol. 59(5) , 332-7, (2005) A simple and rapid analytical procedure for routine quantification of n-C12H25 and n-C14H29 benzalkonium chloride (C-12 and C-14 BKC) homologs in ophthalmic formulations containing antazoline HCl and tetrahydrozoline HCl by high-performance liquid chromatogra... |
|
Serum concentrations in three children with unintentional tetrahydrozoline overdose.
Clin. Toxicol. (Phila.) 49(5) , 434-5, (2011) Major symptoms can occur from tetrahydrozoline (THZ) overdoses in young children, requiring intensive care management. We report three cases that presented with CNS depression and cardiovascular effects where serum concentrations were performed.Case 1 ingeste... |
|
Prolonged cardiovascular effects after unintentional ingestion of tetrahydrozoline.
Clin. Toxicol. (Phila.) 46(2) , 171-2, (2008) Tetrahydrozoline is an imidazoline derivative with alpha receptor agonist activity widely available in over-the-counter topical ocular and nasal formulations. More than 1,600 cases of oral exposures are reported to United States poison centers annually (1,2).... |
|
Use of tetrahydrozoline for chemical submission.
Forensic Sci. Int. 221(1-3) , e12-6, (2012) We report two cases of drug-facilitated sexual assault which presented with CNS depression rendering the victims vulnerable to sexual assault and unable to recall the events surrounding the crimes. In each tetrahydrozoline (THZ) was quantified.Case #1 ingeste... |
|
Gingival inflammatory response induced by chemical retraction agents in beagle dogs.
Int. J. Prosthodont. 15(1) , 14-9, (2002) The aim of this in vivo study on dogs was to investigate and compare the inflammatory potential of four different retraction agents on the gingival connective tissue.All procedures on eight beagle dogs were performed under general anesthesia: taking oral hygi... |
|
Tetrahydrozoline (Visine®) concentrations in serum and urine during therapeutic ocular dosing: a necessary first step in determining an overdose.
Clin. Toxicol. (Phila.) 49(9) , 810-4, (2011) No information exists on therapeutic or toxic concentrations of tetrahydrozoline, which has been reported to be used in drug facilitated sexual assaults. The primary aim of this investigation was to establish baseline therapeutic serum and urine concentration... |