2-Amino-3-(4-hydroxyphenyl)propanehydrazide

2-Amino-3-(4-hydroxyphenyl)propanehydrazide Structure
2-Amino-3-(4-hydroxyphenyl)propanehydrazide structure
Common Name 2-Amino-3-(4-hydroxyphenyl)propanehydrazide
CAS Number 7662-51-3 Molecular Weight 195.218
Density 1.3±0.1 g/cm3 Boiling Point 490.8±40.0 °C at 760 mmHg
Molecular Formula C9H13N3O2 Melting Point 196-198 °C(lit.)
MSDS Chinese USA Flash Point 250.6±27.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase.

J. Med. Chem. 49 , 7532-9, (2006)

Protein tyrosine kinases use two Mg(2+) ions as cofactors in catalysis, one as the ATP-Mg complex (M1) and the other as an essential activator (M2). The M2-binding site has high affinity for transition metal cations such as cobalt and zinc. Taking advantage o...