Triphenylmethanamine

Triphenylmethanamine Structure
Triphenylmethanamine structure
Common Name Triphenylmethanamine
CAS Number 5824-40-8 Molecular Weight 259.345
Density 1.1±0.1 g/cm3 Boiling Point 369.3±0.0 °C at 760 mmHg
Molecular Formula C19H17N Melting Point 102-104 °C(lit.)
MSDS Chinese USA Flash Point 190.9±12.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.

J. Med. Chem. 51 , 1115-25, (2008)

The human kinesin Eg5 is a potential drug target for cancer chemotherapy. Eg5 specific inhibitors cause cells to block in mitosis with a characteristic monoastral spindle phenotype. Prolonged metaphase block eventually leads to apoptotic cell death. S-trityl-...

Triarylmethanes, a new class of cx50 inhibitors.

Front. Pharmacol. 3 , 106, (2012)

The paucity of specific pharmacological agents has been a major impediment for delineating the roles of gap junction (GJ) channels formed by connexin proteins in physiology and pathophysiology. Here, we used the selective optimization of side activities (SOSA...

Novel inhibitors of the Gardos channel for the treatment of sickle cell disease.

J. Med. Chem. 51 , 976-82, (2008)

Sickle cell disease (SCD) is a hereditary condition characterized by deformation of red blood cells (RBCs). This phenomenon is due to the presence of abnormal hemoglobin that polymerizes upon deoxygenation. This effect is exacerbated when dehydrated RBCs expe...

Reaction of triphenylmethylamines with boron trihalides. Ronan RJ, et al.

J. Am. Chem. Soc. 93(25) , 6811-14, (1971)

Tritylamine (triphenylmethylamine) in organic synthesis; II. The reaction of tritylamine with oxiranes-synthesis of N-trityl-ß aminoalcohols. Soroka M and Goldeman W.

ARKIVOC 12 , 31-37, (2003)

Role-allocated combination of two types of hydrogen bonds towards constructing a breathing diamondoid porous organic salt.

Chemistry 19(9) , 3006-16, (2013)

A diamondoid porous organic salt (d-POS) composed of 8-hydroxyquinoline-5-sulfonic acid (HQS) and triphenylmethylamine (TPMA) shows reversible structure contraction and expansion ("breathing") in response to guest desorption and adsorption. This flexible stru...