Estragole
Estragole structure
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Common Name | Estragole | ||
|---|---|---|---|---|
| CAS Number | 140-67-0 | Molecular Weight | 148.202 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 216.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C10H12O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 81.1±0.0 °C | |
| Symbol |
GHS07, GHS08 |
Signal Word | Warning | |
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The natural basil flavonoid nevadensin protects against a methyleugenol-induced marker of hepatocarcinogenicity in male F344 rat.
Food Chem. Toxicol. 74 , 28-34, (2014) The alkenylbenzene methyleugenol occurs naturally in a variety of spices and herbs, including basil, and their essential oils. At high dose levels methyleugenol induces hepatocarcinogenicity in rodents following bioactivation to 1'-sulfooxymethyleugenol which... |
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Five hTRPA1 Agonists Found in Indigenous Korean Mint, Agastache rugosa.
PLoS ONE 10 , e0127060, (2015) Transient receptor potential ankyrin1 (TRPA1) and transient receptor potential vanilloid 1 (TRPV1) are members of the TRP superfamily of structurally related, nonselective cation channels and mediators of several signaling pathways. Previously, we identified ... |
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Design and synthesis of 4-methoxyphenylacetic acid esters as 15-lipoxygenase inhibitors and SAR comparative studies of them.
Bioorg. Med. Chem. 17 , 2327-35, (2009) A group of 4-methoxyphenylacetic acid esters were designed, synthesized and evaluated as potential inhibitors of soybean 15-lipoxygenase (SLO) on the basis of eugenol and esteragol structures. Compounds 7d-e showed the best IC(50) in SLO inhibition (IC(50)=3.... |
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Design, synthesis and SAR studies of 4-allyoxyaniline amides as potent 15-lipoxygensae inhibitors.
Bioorg. Med. Chem. 17 , 1614-22, (2009) A group of 4-allyloxyaniline amides 5a-o were designed, synthesized and evaluated as potential inhibitors of soybean 15-lipoxygenase (SLO) on the basis of eugenol and esteragol structures. Compound 5e showed the best IC(50) in SLO inhibition (IC(50)=0.67+/-0.... |
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Isolation, characterization and evaluation of antimicrobial and cytotoxic activity of estragole, obtained from the essential oil of Croton zehntneri (Euphorbiaceae).
An. Acad. Bras. Ciênc. 87(1) , 173-82, (2015) Croton zehntneri (Euphorbiaceae) is a native aromatic plant from Northeast region of Brazil. The monoterpenoid estragole (ESL) has been isolated by classical chromatographic methods from the essential oil (EO) of C. zehnteneri leaves and characterized by GC-F... |
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Induction of oxidative stress as a possible mechanism of the antifungal action of three phenylpropanoids.
FEMS Yeast Res. 11(1) , 114-22, (2011) The increasing incidence of hospital-acquired infections caused by drug-resistant pathogens, host toxicity, the poor efficacy of drugs and high treatment costs has drawn attention to the potential of natural products as antifungals in mucocutaneous infections... |
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Comparative evaluation of two different Artemisia dracunculus L. cultivars for blood sugar lowering effects in rats.
Phytother Res. 26(4) , 625-9, (2012) Recent concerns about the potential carcinogenicity of estragole and methyleugenol led a number of regulatory bodies to call for restrictions on the use of herbs that contain these constituents. A number of medicinal plants produce essential oils that contain... |
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Chemical composition of the essential oil of Feronia elephantum Correa.
Nat. Prod. Res. 24(19) , 1807-10, (2010) The essential oil composition of Feronia elephantum Correa (family: Rutaceae) was examined by capillary gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS). The analysis revealed the presence of 24 constituents, of which 18 constituents w... |
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Physiologically based biokinetic (PBBK) model for safrole bioactivation and detoxification in rats.
Chem. Res. Toxicol. 24(6) , 818-34, (2011) A physiologically based biokinetic (PBBK) model for alkenylbenzene safrole in rats was developed using in vitro metabolic parameters determined using relevant tissue fractions. The performance of the model was evaluated by comparison of the predicted levels o... |
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Essential oil composition of Foeniculum vulgare Mill. fruits from pharmacies in different countries.
Nat. Prod. Res. 26(13) , 1173-8, (2012) Variations in the essential oil composition of Foeniculum vulgare Mill. commercial fruits obtained from retail pharmacies in Estonia, Norway, Austria and Moldova and from a spice shop in Turkey were determined using capillary GC techniques. The essential oil ... |