Dorzolamide
Dorzolamide structure
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Common Name | Dorzolamide | ||
|---|---|---|---|---|
| CAS Number | 120279-96-1 | Molecular Weight | 324.44 | |
| Density | 1.53 g/cm3 | Boiling Point | 575.8ºC at 760 mmHg | |
| Molecular Formula | C10H16N2O4S3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 302ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Dorzolamide synergizes the antitumor activity of mitomycin C against Ehrlich's carcinoma grown in mice: role of thioredoxin-interacting protein.
Naunyn Schmiedebergs Arch. Pharmacol. 388 , 1271-82, (2015) The antitumor activity of carbonic anhydrase (CA) inhibitors is attributed to their ability to induce a state of intracellular acidification. In fact, acidic intracellular pH was demonstrated to upregulate several tumor suppressor proteins and increase the ac... |
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Synaptic pathology and therapeutic repair in adult retinoschisis mouse by AAV-RS1 transfer.
J. Clin. Invest. 125 , 2891-903, (2015) Strategies aimed at invoking synaptic plasticity have therapeutic potential for several neurological conditions. The human retinal synaptic disease X-linked retinoschisis (XLRS) is characterized by impaired visual signal transmission through the retina and pr... |
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Bleb Analysis and Short-Term Results of Biodegradable Collagen Matrix-Augmented Ahmed Glaucoma Valve Implantation: 6-Month Follow-up.
Invest. Ophthalmol. Vis. Sci. 56 , 5896-903, (2015) To evaluate the short-term efficacy of a biodegradable collagen matrix (BCM) as an adjuvant for Ahmed valve implantation surgery to prevent the hypertensive phase.This prospective study included 43 refractory glaucoma eyes, all followed for 6 months. Refracto... |
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Ability of Bottle Cap Color to Facilitate Accurate Patient-Physician Communication Regarding Medication Identity in Patients with Glaucoma.
Ophthalmology 122 , 2373-9, (2015) To determine the accuracy of patient-physician communication regarding topical ophthalmic medication use based on bottle cap color, particularly among individuals who may have acquired color vision deficiency from glaucoma.Cross-sectional, clinical study.Pati... |
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Matrix Regeneration Therapy: A Case Series of Corneal Neurotrophic Ulcers.
Cornea 35 , 451-5, (2016) Treating corneal neurotrophic ulcers is challenging. Topical application of matrix regeneration therapy (RGTA), which is a dextran derivative polymer and heparan sulfate analog, is a promising regenerative therapy and an alternative or additional therapeutic ... |