![]() Acetyl coenzyme A lithium structure
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Common Name | Acetyl coenzyme A lithium | ||
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CAS Number | 32140-51-5 | Molecular Weight | 827.37000 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C23H35Li3N7O17P3S | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
![]() GHS07 |
Signal Word | Warning |
Choline acetyltransferase mutations cause myasthenic syndrome associated with episodic apnea in humans.
Proc. Natl. Acad. Sci. U. S. A. 98(4) , 2017-22, (2001) Choline acetyltransferase (ChAT; EC ) catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. Mutations in genes encoding ChAT affecting motility exist in Caenorhabditis elegans and Drosophila, but no CHA... |
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Congenital myasthenic syndrome with episodic apnea in patients homozygous for a CHAT missense mutation.
Arch. Neurol. 60(5) , 761-3, (2003) The syndrome of congenital myasthenia with episodic apnea (CMS-EA) was previously found to be due to mutations in the choline acetyltransferase gene (CHAT).To identify the mutations underlying CMS-EA in a Turkish multiplex family.Direct sequencing of the CHAT... |
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Productive infection and bICP0 early promoter activity of bovine herpesvirus 1 are stimulated by E2F1.
J. Virol. 84(13) , 6308-17, (2010) Bovine herpesvirus 1 (BoHV-1) is an important viral pathogen of cattle. Like other members of the subfamily Alphaherpesvirinae, BoHV-1 establishes latency in sensory neurons and has the potential to reactivate from latency. Dexamethasone (DEX) treatment of la... |
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A protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 interacts with Notch1 and Notch3.
J. Virol. 85 , 2536-46, (2011) Like other Alphaherpesvirinae subfamily members, bovine herpesvirus 1 (BHV-1) establishes latency in sensory neurons. The latency-related RNA (LR-RNA) is abundantly expressed in latently infected sensory neurons. An LR mutant virus with stop codons at the ami... |
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Dexamethasone treatment of calves latently infected with bovine herpesvirus 1 leads to activation of the bICP0 early promoter, in part by the cellular transcription factor C/EBP-alpha.
J. Virol. 83 , 8800-9, (2009) Sensory neurons within trigeminal ganglia (TG) are the primary site for bovine herpesvirus 1 (BHV-1) latency. During latency, viral gene expression is restricted to the latency-related (LR) gene and the open reading frame ORF-E. We previously constructed an L... |
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Localization of sequences in a protein (ORF2) encoded by the latency-related gene of bovine herpesvirus 1 that inhibits apoptosis and interferes with Notch1-mediated trans-activation of the bICP0 promoter.
J. Virol. 85 , 12124-33, (2011) Bovine herpesvirus 1 (BHV-1) infection induces clinical symptoms in the upper respiratory tract, inhibits immune responses, and can result in life-threatening secondary bacterial infections. Following acute infection, BHV-1 establishes latency in sensory neur... |
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Choline acetyltransferase 2384G>a polymorphism and the risk of Alzheimer disease.
Alzheimer Dis. Assoc. Disord. 26(1) , 81-7, (2012) The potential association between choline acetyltransferase (CHAT) polymorphism and the risk of Alzheimer disease (AD) has been controversial. We examined the main effect of CHAT polymorphism and its interaction with apolipoprotein E (APOE) polymorphism in th... |
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Role of carnitine acetyltransferases in acetyl coenzyme A metabolism in Aspergillus nidulans.
Eukaryotic Cell 10 , 547-555, (2011) The flow of carbon metabolites between cellular compartments is an essential feature of fungal metabolism. During growth on ethanol, acetate, or fatty acids, acetyl units must enter the mitochondrion for metabolism via the tricarboxylic acid cycle, and acetyl... |
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K-acetylation and its enzymes: overview and new developments.
Handbook of Experimental Pharmacology 206 , 1-12, (2011) Lysine (K) acetylation refers to transfer of the acetyl moiety from acetyl-CoA to the ε-amino group of a lysine residue. This is posttranslational and reversible, with its level dynamically maintained by lysine acetyltransferases (KATs) and deacetylases (KDAC... |
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Nucleosome eviction and activated transcription require p300 acetylation of histone H3 lysine 14.
Proc. Natl. Acad. Sci. U. S. A. 107 , 19254-19259, (2010) Histone posttranslational modifications and chromatin dynamics are inextricably linked to eukaryotic gene expression. Among the many modifications that have been characterized, histone tail acetylation is most strongly correlated with transcriptional activati... |