Iophenoxic acid
Iophenoxic acid structure
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Common Name | Iophenoxic acid | ||
|---|---|---|---|---|
| CAS Number | 96-84-4 | Molecular Weight | 571.91700 | |
| Density | 2.471g/cm3 | Boiling Point | 459ºC at 760mmHg | |
| Molecular Formula | C11H11I3O3 | Melting Point | 146-148ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 231.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Selective analysis of human serum albumin based on SEC-ICP-MS after labelling with iophenoxic acid.
Anal. Bioanal. Chem 407(10) , 2829-36, (2015) Human serum albumin (HSA) is the most abundant protein in the human plasma. HSA has several physiological roles in the human body, including storage and transport. Owing to the predominance of albumin in plasma, HSA is often involved in the protein binding of... |
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Crystallographic analysis reveals the structural basis of the high-affinity binding of iophenoxic acid to human serum albumin.
BMC Struct. Biol. 11 , 18, (2011) Iophenoxic acid is an iodinated radiocontrast agent that was withdrawn from clinical use because of its exceptionally long half-life in the body, which was due in part to its high-affinity binding to human serum albumin (HSA). It was replaced by Iopanoic acid... |
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Liquid chromatography-electrospray ionization mass spectrometry for direct identification and quantification of iophenoxic acid in serum.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 832(1) , 144-57, (2006) A liquid chromatographic-electrospray ionization mass spectrometric technique was developed for direct quantitation of iophenoxic acid (IA) in serum. IA was spiked into canine, feline, bovine, equine, and porcine sera, extracted, and quantified using negative... |
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Evidence for a large and flexible region of human serum albumin possessing high affinity binding sites for salicylate, warfarin, and other ligands.
Mol. Pharmacol. 34(2) , 160-71, (1988) The relations between the single high affinity binding sites for azapropazone, phenylbutazone, chlorpropamide, sulfathiazole, and iophenoxate and the binding regions of human serum albumin represented by the marker ligands diazepam, phenol red, salicylate, an... |
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[Recent triiodinated contrast media for oral cholecystocholangiography].
Med. Radiol. (Mosk.) 30(2) , 58-60, (1985)
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Inhibition of drug binding to human serum albumin by cholecystographic agents.
Il Farmaco 58(9) , 901-8, (2003) The binding of two cholecystographic agents to human serum albumin (HSA) was evaluated by means of two different complementary methodologies. In particular, the inhibition of drug HSA binding caused by iopanoic- and iophenoxic-acid was investigated by circula... |
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Acceptance of simulated oral rabies vaccine baits by urban raccoons.
J. Wildl. Dis. 25(1) , 1-9, (1989) In summer 1986, a study was conducted to evaluate raccoon (Procyon lotor) acceptance of oral baits that could be used for rabies vaccination. One thousand wax-coated sponge bait cubes were filled with 5 mg of a seromarker (iophenoxic acid), placed in polyethy... |
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Plasma marking of arctic foxes with iophenoxic acid.
J. Wildl. Dis. 23(4) , 709-12, (1987) Six arctic foxes (Alopex lagopus) were marked with iophenoxic acid (IA), a substance which elevates concentrations of protein-bound iodine in blood plasma. Buccal absorption of IA was determined by placing 20 mg IA dissolved in 100% ethyl alcohol on the tongu... |
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High-performance liquid chromatographic determination of iophenoxic acid in serum.
J. Chromatogr. B, Biomed. Appl. 654(2) , 293-6, (1994) Iophenoxic acid (IPA), a marker used to investigate the feeding behaviour of bait-consuming animals has previously been indirectly determined by measuring protein-bound iodine levels in serum or plasma. For the first time a method is reported for the direct d... |
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Analysis by LC/ESI-MS of iophenoxic acid derivatives and evaluation as markers of oral baits to deliver pharmaceuticals to wildlife.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878(22) , 1997-2002, (2010) Iophenoxic acid and its derivatives (methyl, ethyl, and propyl) are organic chemicals used as markers in baiting campaigns to deliver vaccines, pharmaceuticals, contraceptives or poisons to wildlife. In this study we develop a method of detection of IPA deriv... |