vasicine
vasicine structure
|
Common Name | vasicine | ||
|---|---|---|---|---|
| CAS Number | 6159-55-3 | Molecular Weight | 188.226 | |
| Density | 1.1124 | Boiling Point | 373.8±52.0 °C at 760 mmHg | |
| Molecular Formula | C11H12N2O | Melting Point | 211.5°C | |
| MSDS | Chinese USA | Flash Point | 179.9±30.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Potentiation of oxytocin evoked responses by (+) sotalol deoxysotalol and Vasicine HCl on isolated rat and rabbit uterus.
Indian J. Med. Res. 76 Suppl , 107-14, (1982)
|
|
|
Natural products as templates for bioactive compound libraries: part 2. Novel modifications of vasicine (peganine) core via efficient and regioselective generation of 3-lithiodeoxyvasicine and its stereoselective addition to aliphatic ketones section sign.
Nat. Prod. Res. 20(9) , 871-81, (2006) A general procedure for direct lithiation of deoxyvasicine was developed. 3-Lithiodeoxyvasicine intermediate was found to react with various aliphatic ketones providing derivatives of 3-(hydroxyalkyl)deoxyvasicine in good yields. Similar reaction with 4-alkyl... |
|
|
Formulation and pharmacokinetic evaluation of hard gelatin capsule encapsulating lyophilized Vasa Swaras for improved stability and oral bioavailability of vasicine.
Fitoterapia 82(3) , 446-53, (2011) The oral bioavailability of vasicine (1) was investigated in hard gelatin capsules of lyophilized Vasa Swaras (aqueous extract of Adhatoda vasica Nees.,Fam.: Acanthaceae) The rat pharmacokinetic profile of lyophilized Vasa Swaras, Vasa Swaras, vasicine (1) (c... |
|
|
Thrombopoietic activity of vasicine hydrochloride.
Indian J. Exp. Biol. 20(9) , 704-9, (1982)
|
|
|
Detection and confirmation of alkaloids in leaves of Justicia adhatoda and bioinformatics approach to elicit its anti-tuberculosis activity.
Appl. Biochem. Biotechnol. 168(5) , 980-90, (2012) The extraction and determination of alkaloids was performed and confirmed by phytochemical analysis. Six different quinazoline alkaloids (vasicoline, vasicolinone, vasicinone, vasicine, adhatodine and anisotine) were found in the leaf of Justicia adhatoda (J.... |
|
|
Chronic toxicity studies with vasicine from Adhatoda vasica Nees. in rats and monkeys.
Indian J. Exp. Biol. 25(7) , 467-70, (1987)
|
|
|
Enzyme inhibition, antioxidant and antibacterial potential of vasicine isolated from Adhatoda vasica Nees.
Pak. J. Pharm. Sci. 25 , 651-6, (2012) Vasicine (1) was isolated from the ethanolic extract of Adhatoda vasica Nees (Acanthaceae) and the structure was confirmed using spectroscopic techniques. Acetylcholine esterase, trypsin, DPPH inhibition potential and FRAP assay were carried out using in vitr... |
|
|
Quantitative determination of vasicine and vasicinone in Adhatoda vasica by high performance capillary electrophoresis.
Pharmazie 63(1) , 20-2, (2008) A new method of capillary electrophoresis was developed for the quantitative determination of vasicine and vasicinone from Adhatoda vasica (L.) Nees. The electrophoretic separation was performed using a 47 cm x 50 microm ID (38.5 cm effective length) fused si... |
|
|
Cytotoxicity of alkaloids isolated from Peganum harmala seeds.
Pak. J. Pharm. Sci. 26(4) , 699-706, (2013) Peganum harmala is used in traditional medicine to treat a number of diseases including cancer. Our preliminary studies show that the alkaloidal extract of PH seed is cytotoxic to several tumor cell lines in vitro and has antitumor effect in a tumor model in ... |
|
|
Pharmacokinetics of vasicine in healthy Indian volunteers.
Zhongguo Yao Li Xue Bao 8(2) , 190-2, (1987)
|