Clofilium tosylate

Clofilium tosylate Structure
Clofilium tosylate structure
Common Name Clofilium tosylate
CAS Number 92953-10-1 Molecular Weight 510.172
Density N/A Boiling Point N/A
Molecular Formula C28H44ClNO3S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Block of heart potassium channels by clofilium and its tertiary analogs: relationship between drug structure and type of channel blocked.

Mol. Pharmacol. 34 , 60-66, (1988)

The whole-cell arrangement of the patch clamp was used to study delayed rectifier and inward rectifier K channels in isolated guinea pig ventricular cells. Block of these channels by an externally applied quaternary nitrogen compound, clofilium, and two of it...

The differential response of normal and ischaemic Purkinje fibres to clofilium, d-sotalol and bretylium.

Cardiovasc. Res. 23 , 554-559, (1989)

To determine whether ischaemic tissue is more sensitive than normal tissue to class III anti-arrhythmic agents, we studied the effects of the class III agents clofilium, d-sotalol and bretylium on normal and ischaemic Purkinje fibres one day after ligation of...

Clofilium and other class III agents. Steinberg, et al., Williams, et al.

Handbook of Experimental Pharmacology Berlin Heidelberg 89 , 389, (1989)