(+)-DIACETYL-L-TARTARIC ANHYDRIDE
(+)-DIACETYL-L-TARTARIC ANHYDRIDE structure
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Common Name | (+)-DIACETYL-L-TARTARIC ANHYDRIDE | ||
|---|---|---|---|---|
| CAS Number | 6283-74-5 | Molecular Weight | 216.14500 | |
| Density | 1.43g/cm3 | Boiling Point | 350.6ºC at 760 mmHg | |
| Molecular Formula | C8H8O7 | Melting Point | 130-135ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 158.2ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Enantioselective drug monitoring of (R)- and (S)- propranolol in human plasma via derivatization with optically active (R,R)-O,O-diacetyl tartaric acid anhydride.
J. Chromatogr. A. 487 , 375, (1989) A sensitive high-performance liquid chromatographic method was developed for the stereoselective assay of (R)- and (S)-propranolol in human plasma. The method involves diethyl ether extraction of the drugs and a racemic internal standard, N-tert.-butylpropran... |
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Analytical and semi-preparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers.
J. Chromatogr. A. 581(1) , 83-92, (1992) (+/-)-Hydroxychloroquine (HCQ) is an antimalarial and anti-arthritic drug which is administered as the racemate. An accurate, precise and sensitive high-performance liquid chromatographic assay was developed for the determination of HCQ enantiomers in samples... |
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Measurement of urinary D- and L-2-hydroxyglutarate enantiomers by stable-isotope-dilution liquid chromatography-tandem mass spectrometry after derivatization with diacetyl-L-tartaric anhydride.
Clin. Chem. 50(8) , 1391-5, (2004) The differential diagnosis of D-2-hydroxyglutaric aciduria (D-2-HGA), L-2-hydroxyglutaric aciduria (L-2-HGA), and the combined D/L-2-hydroxyglutaric aciduria (D/L-2-HGA) can be accomplished only by the measurement of the corresponding 2-hydroxyglutarate (2-HG... |
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Improved separation of diastereomeric derivatives of enantiomers by a physical network of linear polyvinylpyrrolidone applied as pseudophase in capillary zone electrophoresis.
Electrophoresis 15(6) , 769-73, (1994) Diastereomeric analytes were separated using capillary zone electrophoresis with polyvinylpyrrolidone as polymeric additive to the buffer solution. As test substances derivatives of D- and L- alpha-amino and alpha-hydroxy acids formed by reaction with (+)-O,O... |
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2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations.
PLoS ONE 6 , e16812, (2011) Gliomas frequently contain mutations in the cytoplasmic NADP(+)-dependent isocitrate dehydrogenase (IDH1) or the mitochondrial NADP(+)-dependent isocitrate dehydrogenase (IDH2). Several different amino acid substitutions recur at either IDH1 R132 or IDH2 R172... |
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A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma.
J. Pharm. Biomed. Anal. 13(7) , 911-8, (1995) A stereospecific liquid chromatographic (LC) assay was developed for the quantification of the antimalarial drug, halofantrine, in human plasma. Following protein precipitation with acetonitrile, the enantiomers of halofantrine were extracted from human plasm... |
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W. Lindner et al.
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Y. Dobashi, S. Hara
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K.H. Bell
Aust. J. Chem. 34 , 671, (1981)
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