NU1025

NU1025 Structure
NU1025 structure
Common Name NU1025
CAS Number 90417-38-2 Molecular Weight 176.172
Density 1.4±0.1 g/cm3 Boiling Point 345.4±44.0 °C at 760 mmHg
Molecular Formula C9H8N2O2 Melting Point 253-258ºC
MSDS Chinese USA Flash Point 162.7±28.4 °C
Symbol GHS07
GHS07
Signal Word Warning

Rapamycin-resistant poly (ADP-ribose) polymerase-1 overexpression is a potential therapeutic target in lymphangioleiomyomatosis.

Am. J. Respir. Cell. Mol. Biol. 51(6) , 738-49, (2014)

Lymphangioleiomyomatosis (LAM) is a female-predominant cystic lung disease that can lead to respiratory failure. LAM cells typically have inactivating tuberous sclerosis complex 2 (TSC2) mutations and mammalian target of rapamycin (mTOR) complex (mTORC) 1 act...