3-(Trimethylsilyl)propionic-2,2,3,3-d4 acid sodium salt
3-(Trimethylsilyl)propionic-2,2,3,3-d4 acid sodium salt structure
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Common Name | 3-(Trimethylsilyl)propionic-2,2,3,3-d4 acid sodium salt | ||
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| CAS Number | 24493-21-8 | Molecular Weight | 172.26600 | |
| Density | N/A | Boiling Point | 223.6ºC at 760 mmHg | |
| Molecular Formula | C6H9D4NaO2Si | Melting Point | 300°C | |
| MSDS | USA | Flash Point | 89ºC | |
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A metabolomic study of adipose tissue in mice with a disruption of the circadian system.
Mol. Biosyst. 11 , 1897-906, (2015) Adipose tissue functions in terms of energy homeostasis as a rheostat for blood triglyceride, regulating its concentration, in response to external stimuli. In addition it acts as a barometer to inform the central nervous system of energy levels which can var... |
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Ethanol contamination of cerebrospinal fluid during standardized sampling and its effect on (1)H-NMR metabolomics.
Anal. Bioanal. Chem 407 , 4835-9, (2015) Standardization of body fluid sampling, processing and storage procedures is pivotal to ensure data quality in metabolomics studies. Yet, despite strict adherence to standard sampling guidelines, we detected variable levels of ethanol in the (1)H-NMR spectra ... |
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Water Proton NMR for In Situ Detection of Insulin Aggregates.
J. Pharm. Sci. 104 , 4132-41, (2016) The need for quality control during the manufacturing and distribution of biopharmaceuticals is becoming increasingly necessary. At present, detecting drug degradation through the monitoring of active factor aggregation is accomplished through "invasive" tech... |
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The antitumor effect of formosanin C on HepG2 cell as revealed by 1H-NMR based metabolic profiling.
Chem. Biol. Interact. 220 , 193-9, (2014) Formosanin C (FC) is a pure compound isolated from Rhizoma Paridis. In the past years, antitumor effects of FC have been observed in several cultural cells and animal systems. However, there was no research particular on liver cancer. In this experiment, 3-(4... |
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Metabolomics reveals the metabolic shifts following an intervention with rye bread in postmenopausal women--a randomized control trial.
Nutr. J. 11 , 88, (2012) Epidemiological studies have consistently shown that whole grain (WG) cereals can protect against the development of chronic diseases, but the underlying mechanism is not fully understood. Among WG products, WG rye is considered even more potent because of it... |
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Quorum Sensing Is Accompanied by Global Metabolic Changes in the Opportunistic Human Pathogen Pseudomonas aeruginosa.
J. Bacteriol. 197 , 2072-82, (2015) Pseudomonas aeruginosa uses N-acyl-homoserine lactone (AHL)-dependent quorum sensing (QS) systems to control the expression of secreted effectors. These effectors can be crucial to the ecological fitness of the bacterium, playing roles in nutrient acquisition... |
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¹³C SPE MAS measurement of ligand concentration in compressible chromatographic beads.
Magn. Reson. Chem. 53 , 572-7, (2015) A method for measuring the ligand concentration in heterogeneous materials like chromatography media is described. In this method, (13)C single pulse excitation magic angle spinning NMR experiment with broadband (1)H decoupling is used to determine the peak i... |
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Analysis of the (Trimethylsilyl)propionic Acid-β(12-28) Peptide Binding Equilibrium with NMR Spectroscopy.
Anal. Chem. 11th ed., 71 , 2117, (1999) The binding of a small molecule, (trimethylsilyl)propionic acid (TSP), to a 17-residue peptide, β(12-28), is examined using (1)H NMR spectroscopy. β(12-28) (VHHQKLVFFAEDVGSNK) is a central fragment of the 40-42-residue Alzheimer's-associated Aβ peptide. This ... |
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Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet.
Metabolites 2 , 366-81, (2014) The peroxisome proliferator-activated receptor-γ coactivators (PGC-1) are transcriptional coactivators with an important role in mitochondrial biogenesis and regulation of genes involved in the electron transport chain and oxidative phosphorylation in oxidati... |
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Identification of Binding Mode of a Platinum (II) Complex, PtCl(2)(DIP), and Calf Thymus DNA.
Bioinorg. Chem. Appl. 2011 , 687571, (2011) The Pt(II) complex, PtCl(2)(DIP) (DIP = chelating dinitrogen ligand: 4,7-diphenyl-1,10-phenanthroline), was synthesized and characterized by elemental analysis (CHN) and (1)H NMR and UV-vis techniques. The binding of this complex to calf thymus DNA was invest... |