Trichostatin A
Trichostatin A structure
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Common Name | Trichostatin A | ||
|---|---|---|---|---|
| CAS Number | 58880-19-6 | Molecular Weight | 302.368 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C17H22N2O3 | Melting Point | 141-143ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.
PLoS Pathog. 11(2) , e1004621, (2015) Helicobacter pylori persistently colonizes the human stomach, with mixed roles in human health. The CagA protein, a key host-interaction factor, is translocated by a type IV secretion system into host epithelial cells, where its EPIYA tyrosine phosphorylation... |
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Preservative activity of lavender hydrosols in moisturizing body gels.
Lett. Appl. Microbiol. 60(1) , 27-32, (2014) The study was undertaken to verify the antimicrobial activity of Lavandula angustifolia hydrosols in moisturizing body gels. The inhibition efficacy of four lavender hydrosols (obtained from fresh or dry herbs or flowers) was tested against Staphylococcus aur... |
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Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.
PLoS ONE 10(4) , e0123460, (2015) Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransferase is an enzyme that is highly upregulated in ventilator-i... |
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Wild-type and specific mutant androgen receptor mediates transcription via 17β-estradiol in sex hormone-sensitive cancer cells.
J. Cell Physiol. 230(7) , 1594-606, (2015) We previously encountered regulatory processes wherein dihydrotestosterone (DHT) exerted its inhibitory effect on parathyroid hormone-related protein (PTHrP) gene repression through the estrogen receptor (ER)α, but not the androgen receptor (AR), in breast ca... |
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Dual-species relations between Candida tropicalis isolated from apple juice ultrafiltration membranes, with Escherichia coli O157:H7 and Salmonella sp.
J. Appl. Microbiol. 118(2) , 431-42, (2015) The objective of this study was to determine the interactions between common spoilage yeast, Candida tropicalis, isolated from ultrafiltration membranes, and Escherichia coli O157:H7 and Salmonella sp. on stainless steel surfaces.Single and dual-species attac... |
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Loss of TGFβ Receptor Type 2 Expression Impairs Estrogen Response and Confers Tamoxifen Resistance.
Cancer Res. 75(7) , 1457-69, (2015) One third of the patients with estrogen receptor α (ERα)-positive breast cancer who are treated with the antiestrogen tamoxifen will either not respond to initial therapy or will develop drug resistance. Endocrine response involves crosstalk between ERα and T... |
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The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition.
Nucleic Acids Res. 43(1) , 162-78, (2015) The loss of the tumour suppressor E-cadherin (Cdh1) is a key event during tumourigenesis and epithelial-mesenchymal transition (EMT). Transforming growth factor-β (TGFβ) triggers EMT by inducing the expression of non-histone chromatin protein High Mobility Gr... |
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The efficacy of short and repeated high-pressure processing treatments on the reduction of non-O157:H7 Shiga-toxin producing Escherichia coli in ground beef patties.
Meat Science 102 , 22-6, (2015) High pressure processing (HPP) has previously been shown to be effective at reducing Escherichia coli O157:H7 in meat products. However, few studies have determined whether HPP may be effective at reducing non-O157:H7 Shiga toxin-producing E. coli (STEC) in g... |
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Fungal metabolite myriocin promotes human herpes simplex virus-2 infection.
Life Sci. 120 , 31-8, (2015) Myriocin is a fungal metabolite with antiviral activity, including influenza, hepatitis B, and hepatitis C viruses. We investigated whether myriocin has activity against human HSV-2, one of the most prevalent pathogens of sexually transmitted disease.Cell cul... |
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Hydrogenophaga luteola sp. nov. isolated from reed pond water.
Antonie van Leeuwenhoek 108 , 695-701, (2015) A yellowish colored, Gram-staining negative, strictly aerobic, motile, rod-shaped bacterium, designated THG-SQE7(T), was isolated from reed pond water in Shangqiu, PR China. Comparative 16S rRNA gene sequence analysis indicated that strain THG-SQE7(T) is most... |