2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione

2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione Structure
2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione structure
Common Name 2-Hydroxy-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione
CAS Number 5596-17-8 Molecular Weight 181.145
Density 1.7±0.1 g/cm3 Boiling Point 384.8±52.0 °C at 760 mmHg
Molecular Formula C8H7NO4 Melting Point 194ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 186.5±30.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Fluorous tagged N-hydroxy phthalimide for the parallel synthesis of O-aryloxyamines.

J. Comb. Chem. 12 , 655-658, (2010)

The parallel synthesis of O-aryloxyamines remains an unfulfilled need in the field of medicinal chemistry and fragment-based approaches. To fill this gap a solution-phase two-step process based on (1) a copper-catalyzed cross-coupling of aryl boronic acids wi...