1-Isothiocyanatoadamantane

1-Isothiocyanatoadamantane Structure
1-Isothiocyanatoadamantane structure
Common Name 1-Isothiocyanatoadamantane
CAS Number 4411-26-1 Molecular Weight 193.309
Density 1.4±0.1 g/cm3 Boiling Point 297.6±7.0 °C at 760 mmHg
Molecular Formula C11H15NS Melting Point 166-168 °C(lit.)
MSDS Chinese USA Flash Point 138.0±26.0 °C
Symbol GHS07
GHS07
Signal Word Warning

7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies.

Molecules 18(2) , 2397-418, (2013)

A structural series of 7-MEOTA-adamantylamine thioureas was designed, synthesized and evaluated as inhibitors of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE). The compounds were prepared based on the multi-target-directed ligand ...

Synthesis and structural characterization of tris(2-mercapto-1-adamantylimidazolyl)hydroborato complexes: a sterically demanding tripodal [S3] donor ligand.

Inorg. Chem. , (2011)

The tris(2-mercapto-1-adamantylimidazolyl)hydroborato ligand, [Tm(Ad)], has been synthesized via the reaction of 1-adamantyl-2-mercaptoimidazole with MBH(4) (M = Li, K). [Tm(Ad)]M has been used to synthesize a variety of compounds of the main-group and transi...

[Antiviral agents / 9th communication: virustatically active N-(1-adamantyl)-thiourea derivatives based on cyclic secondary amines (author's transl)].

Arzneimittelforschung 27(5) , 969-72, (1977)

By nucleophilic addition of pyrrolidine (2a), piperidine (2b), 3-hydroxypiperidine (2c), and 4-hydroxypiperidine (2d) on 1-adamantyl-isothiocyanate (1), the N',N'-disubstituted N-(1-adamantyl)-thiourea derivatives 3a, 3b, 3c, and 3d are accessible. Particular...