2,4-Xylidine
2,4-Xylidine structure
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Common Name | 2,4-Xylidine | ||
|---|---|---|---|---|
| CAS Number | 95-68-1 | Molecular Weight | 121.180 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 214.7±9.0 °C at 760 mmHg | |
| Molecular Formula | C8H11N | Melting Point | 16 °C | |
| MSDS | Chinese USA | Flash Point | 90.6±0.0 °C | |
| Symbol |
GHS06, GHS08, GHS09 |
Signal Word | Danger | |
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cIEF for rapid pKa determination of small molecules: a proof of concept.
Eur. J. Pharm. Sci. 63 , 14-21, (2014) A capillary isoelectric focusing (cIEF) method was developed for the determination of the ionization constants (pKa) of small molecules. Two approaches used to decrease the electroosmotic flow (EOF) were compared: (i) a hydroxypropylcellulose (HPC) coated cap... |
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Stability of erythrocyte membrane and overall hemostasis potential - A biocompatibility study of mebrofenin and other iminodiacetic acid derivatives.
Pharmacol. Rep. 67 , 1230-9, (2015) Intravenous injection seems to be the most convenient way of administering drugs and contrast agents, which makes components of the blood the first and usually unwanted target of their action. Binding of intravenously administered compounds to erythrocytes, b... |
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Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography—Electrospray ionization tandem mass spectrometry
J. Chromatogr. A. 1216(41) , 6970-3, (2009) The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will help in identifying the environmental sources of such expos... |
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Determination method for xylidines in workplace air.
J. Occup. Health 53(3) , 230-3, (2011) The purpose of this research was to develop a determination method for xylidines (XLDs) in workplace air for risk assessment.The characteristics of the proposed method, such as recovery, detection limit, reproducibility, and storage stability of the samples w... |
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Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora.
Appl. Environ. Microbiol. 73(23) , 7759-62, (2007) The rates of metabolism of Sudan I and II and Para Red by human intestinal microflora were high compared to those of Sudan III and IV under anaerobic conditions. Metabolites of the dyes were identified as aniline, 2,4-dimethylaniline, o-toluidine, and 4-nitro... |
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Liquid phase overtone spectral investigations of 2,6-dimethylaniline and 2,4-dimethylaniline-evidence for steric nature of the ortho effect and the consequent base weakening.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 60(10) , 2337-41, (2004) The near infrared vibrational overtone absorption spectrum of liquid phase 2,6-dimethylaniline and 2,4-dimethylaniline are reported in the region deltanu = 2, 3 and 4. The aryl CH, methyl CH and NH local mode mechanical frequency values obtained from fitting ... |
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Oxidative degradation of 2,4-xylidine by photosensitization with 2,4,6-triphenylpyrylium: homogeneous and heterogeneous catalysis.
Chemosphere 57(9) , 1123-30, (2004) The possibility of using zeolites containing the 2,4,6-triphenylpyrylium cation as photocatalysts for the degradation of pollutants has been tested on aqueous xylidine (2,4-dimethylaniline) solutions as models for contaminated wastewaters. The influence of th... |
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Metabolic activation of 2,4-xylidine and its mutagenic metabolite.
Biochem. Pharmacol. 32(4) , 735-8, (1983)
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Assessment of aniline derivatives-induced DNA damage in the liver cells of B6C3F1 mice using the alkaline single cell gel electrophoresis ("comet") assay.
Teratog. Carcinog. Mutagen. 19(5) , 323-7, (1999) The alkaline single cell gel electrophoresis (SCGE) or "comet" assay under alkaline conditions was used to measure DNA damage in the liver cells of B6C3F1 male mice exposed to 2,4-dimethylaniline and 2, 4,6-trimethylaniline. Cells embedded in agarose were lys... |
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Electrochemical investigation of the effect of pH and solvent on amitraz stability.
J. Agric. Food Chem. 54(21) , 8139-43, (2006) The widespread use of the pesticide amitraz for pest control of crops, livestock and honeybees has warranted several studies aimed at understanding the degradation of this compound during storage and use. In particular the degradation of amitraz and the natur... |