osajin

osajin Structure
osajin structure
Common Name osajin
CAS Number 482-53-1 Molecular Weight 404.455
Density 1.3±0.1 g/cm3 Boiling Point 632.3±55.0 °C at 760 mmHg
Molecular Formula C25H24O5 Melting Point 189° (uncorr), 193° (corr)
MSDS Chinese USA Flash Point 218.7±25.0 °C
Symbol GHS09
GHS09
Signal Word Warning

Interactions of genistein and related isoflavones with lipid micelles.

Langmuir 22(17) , 7175-84, (2006)

Genistein (5,7,4'-trihydroxyisoflavone) modulates the function of several transmembrane ion-channel proteins by mechanisms that are unrelated to phosphorylation events. Daidzein (7,4'-dihydroxy-isoflavone) typically exhibits modest effects, whereas genistin (...

Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide.

J. Pharm. Biomed. Anal. 48(1) , 127-33, (2008)

The antioxidant properties of pomiferin, isopomiferin, osajin and catalposide are evaluated. The electrochemical behaviour of these compounds at a carbon paste electrode was studied using square wave voltammetry. Oxidative signals, optimized frequencies and a...

Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera.

Bioorg. Med. Chem. Lett. 17(17) , 4753-5, (2007)

The major constituents from the fruits of Maclura pomifera are the prenylated isoflavones, osajin (1) and pomiferin (2). Their structures were elucidated using NMR spectroscopic techniques and mass spectrometric analysis. Compound 2 showed potential inhibitor...

Activation of multiple apoptotic pathways in human nasopharyngeal carcinoma cells by the prenylated isoflavone, osajin.

PLoS ONE 6(4) , e18308, (2011)

Osajin is a prenylated isoflavone showing antitumor activity in different tumor cell lines. The underlying mechanism of osajin-induced cancer cell death is not clearly understood. In the present study, the mechanisms of osajin-induced cell death of human naso...

Examining the genomic influence of skin antioxidants in vitro.

Mediators Inflamm. 2010 , 230450, (2010)

A series of well-known, purified antioxidants including: Resveratrol, Epigallocatechin Gallate (EGCG), Genistein, Rosavin, Puerarin, Chlorogenic Acid, Propolis and two newer unexplored isoflavonoids isolated from Maclura pomifera (Osage Orange) including Pomi...

Protective effects of osajin in ischemia-reperfusion of laboratory rat kidney.

Pharmazie 61(6) , 552-5, (2006)

The aim of this study was to analyze the antioxidative effect of osajin during prophylactic administration. The pathological model for in vivo experiment was the unilateral ischemia-reperfusion of kidney of the laboratory rat. The animals were randomly divide...