LORMETAZEPAM

LORMETAZEPAM Structure
LORMETAZEPAM structure
Common Name LORMETAZEPAM
CAS Number 848-75-9 Molecular Weight 335.18500
Density 1.44 g/cm3 Boiling Point 575.8ºC at 760mmHg
Molecular Formula C16H12Cl2N2O2 Melting Point 163-168ºC
MSDS N/A Flash Point 302.1ºC
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

Gender differences in highway driving performance after administration of sleep medication: a review of the literature.

Traffic Inj. Prev. 13(3) , 286-92, (2012)

It is generally assumed that there are minimal gender differences in the safety and efficacy of central nervous system drugs, as is evidenced by men and women receiving the same drug dosage. There is, however, evidence that drugs may have a differential effec...

Quantification of lorazepam and lormetazepam in human breast milk using GC-MS in the negative chemical ionization mode.

J. Anal. Toxicol. 31(4) , 224-6, (2007)

Lormetazepam (Loramet is a benzodiazepine mainly used as an hypnotic to treat insomnia. Lorazepam (Temesta) is used as an anxiolytic, tranquilizer, sedative, and anticonvulsant, and it is the major metabolite of lormetazepam. In this study, we designed a meth...

Sexual assault under benzodiazepine submission in a Paris suburb.

Arch. Gynecol. Obstet. 263(4) , 193-7, (2000)

Sexual assaults under benzodiazepine submission have been described, since use of benzodiazepine enables non consensual sexual activity but rarely fully reported. An accurate evaluation of the phenomenon has seemed interesting. Files of 23 adult males and fem...

Role of lormetazepam in the treatment of insomnia in the elderly.

Clin. Drug Investig. 27(5) , 325-32, (2007)

Sleep architecture changes with age, both in terms of efficiency and total duration of sleep. Hypnotic benzodiazepines promote rapid onset of sleep, uninterrupted sleep and longer duration of sleep in the absence of carryover sedation the following morning; t...

Psychomotor performance in healthy young adult volunteers peceiving lormetazepam and placebo: A single-dose, randomized, double-blind, crossover trial

Clin. Ther. 27(1) , 78-83, (2005)

Background: Lormetazepam is a hypnotic benzodiazepinecurrently used in the treatment of insomnia. When this agent is used appropriately, its pharmacologic properties predict a high therapeutic index with a good tolerability profile.

Lormetazepam effects on daytime vigilance, psychomotor performance and simulated driving in young adult healthy volunteers.

Int. J. Clin. Pharmacol. Ther. 40(7) , 304-9, (2002)

To assess the residual effects of lormetazepam on daytime vigilance, psychomotor performance and simulated driving in adult healthy volunteers.Twelve subjects (7 women, 5 men), aged 27 - 38 years (mean 31).Subjects received lormetazepam 1 mg tablet and placeb...

A randomized clinical trial comparing doses and efficacy of lormetazepam tablets or oral solution for insomnia in a general practice setting.

Hum. Psychopharmacol. Clin. Exp. 19(2) , 129-34, (2004)

Lormetazepam is a short-acting benzodiazepine hypnotic which is beneficial in shortening the time to onset of sleep. The aim of the study was to assess a new formulation of lormetazepam (oral solution) in comparison with lormetazepam tablets in out-patients w...

Conversion visual loss: a differential diagnosis in infant amblyopia.

Eur. J. Ophthalmol. 19(6) , 1065-8, (2009)

To report the first case of amblyopia due to a conversion disorder in a child.A 9-year-old girl without allergies or family or personal antecedents of interest presented to our clinic. She manifested a progressive visual loss after an episode of lumbar pain. ...

[Benzodiazepine and hiccup: three case reports].

Therapie. 60(1) , 57-60, (2005)

Hiccup is a sudden contraction of the inspiratory muscles, followed by an abrupt closure of the glottis, thus producing a characteristic sound. In the literature, some drugs have been reported to induce hiccup. We discuss three case reports after administrati...

[Paroxetine-induced severe hyponatremic rhabdomyolisis].

Med. Intensiva 32(7) , 365-6, (2008)