methaqualone
methaqualone structure
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Common Name | methaqualone | ||
|---|---|---|---|---|
| CAS Number | 72-44-6 | Molecular Weight | 250.29500 | |
| Density | 1.16g/cm3 | Boiling Point | 406.9ºC at 760 mmHg | |
| Molecular Formula | C16H14N2O | Melting Point | 120ºC | |
| MSDS | N/A | Flash Point | 9℃ | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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Blockbusters and controlled substances: Miltown, Quaalude, and consumer demand for drugs in postwar America.
Stud. Hist. Philos. Biol. Biomed. Sci. 42(4) , 415-26, (2011) In 1955 Carter Products launched its new tranquilizer Miltown with a huge marketing blitz; Miltown soon became one of America's earliest "blockbuster" celebrity drugs. In 1981, federal agents shut down a network of "stress clinics" and arrested the owners, me... |
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Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists.
Bioorg. Med. Chem. Lett. 10(11) , 1203-5, (2000) Quinazolin-4-one derivatives of methaqualone substituted at C-2 define a new class of noncompetitive antagonists at AMPA receptors. |
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Cannabis and other drug use among trauma patients in three South African cities, 1999-2001.
S. Afr. Med. J. 95(6) , 429-32, (2005) To assess the extent of cannabis and other drug use among patients presenting with recent injuries at trauma units in Cape Town, Port Elizabeth and Durban from 1999 to 2001.Cross-sectional surveys were conducted during a 4-week period at each of the above sit... |
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Inhibition of translocation of nascent apolipoprotein B across the endoplasmic reticulum membrane is associated with selective inhibition of the synthesis of apolipoprotein B.
J. Biol. Chem. 275(35) , 27399-405, (2000) In HepG2 cells, inhibition of apolipoprotein B100 (apoB) translocation across the endoplasmic reticulum by an microsomal triglyceride transfer protein (MTP) inhibitor (CP-10447) in the presence of N-acetyl-leucinyl-norleucinal, a proteasomal inhibitor, result... |
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A survey of reported synthesis of methaqualone and some positional and structural isomers.
Forensic Sci. Int. 122(2-3) , 142-9, (2001) Methaqualone (2-methyl-3-o-tolyl-4(3H)-quinazolinone) is the illicit synthetic drug of choice amongst South African drug users. Historically police and forensic investigation has proven that all methaqualone seized by the South African Police Service originat... |
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Toxicological screening for drugs of abuse in samples adulterated with household chemicals.
S. Afr. Med. J. 92(7) , 547-9, (2002) Urine samples that tested positive for two drugs of abuse, namely cannabis and methaqualone, were reassayed in the presence or absence of common household chemicals: Jik (sodium hypochlorite), Dettol (chloroxylenol), G-cide Plus (glutaraldehyde), Perle Hand S... |
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Solid-phase extraction and HPLC analysis of kebuzone and its metabolites in blood.
Pharmazie 51(9) , 651-3, (1996) A HPLC method for quantification of kebuzone and its metabolites in whole blood was developed. The compounds and the internal standard were isolated from blood by solid-phase extraction on a C-18 cartridge. A blood sample was to be hemolyzed before extraction... |
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A case of lethal intoxication after ingestion of toquilone compositum.
Am. J. Forensic Med. Pathol. 17(3) , 231-2, (1996) A case of acute intoxication of both methaqualone and diphenhydramine is reported. The analysis of these compounds was performed by liquid-liquid extraction (Toxi-Lab DPC procedure) followed by gas chromatography/mass spectrometry determination; both substanc... |
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Phenytoin intoxication induced by Mandrax (methaqualone).
Epilepsy Res. 98(2-3) , 281-2, (2012)
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Antimalarials: shortages and searches.
Mol. Interv. 5(5) , 268-72, (2005)
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