COCAETHYLENE
COCAETHYLENE structure
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Common Name | COCAETHYLENE | ||
|---|---|---|---|---|
| CAS Number | 529-38-4 | Molecular Weight | 317.38000 | |
| Density | 1.2g/cm3 | Boiling Point | 408.8ºC at 760mmHg | |
| Molecular Formula | C18H23NO4 | Melting Point | 109ºC | |
| MSDS | Chinese USA | Flash Point | 201ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Cleaning up blood samples using a modified "QuEChERS" procedure for the determination of drugs of abuse and benzodiazepines by UPLC-MSMS(☆).
Forensic Sci. Int. 243 , 99-106, (2014) The "QuEChERS" (quick, easy, cheap, effective, rugged, and safe) dispersive SPE (dSPE) method is an emerging sample preparation technique that is becoming increasingly popular in the area of multi-residue pesticide analysis in food and agricultural products. ... |
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A direct immersion solid-phase microextraction gas chromatography/mass spectrometry method for the simultaneous detection of levamisole and minor cocaine congeners in hair samples from chronic abusers.
Ther. Drug Monit. 36(6) , 789-95, (2014) Because levamisole has been increasingly found as a component of illicit drugs, a robust method to detect its presence in hair samples is needed. However, no systematic research on the detection of levamisole in hair samples has been published. The method pre... |
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Urine Mescaline Screening With a Biochip Array Immunoassay and Quantification by Gas Chromatography-Mass Spectrometry.
Ther. Drug Monit. 37 , 805-11, (2015) Mescaline, the primary psychoactive chemical in peyote cactus, has been consumed for thousands of years in ancient religious ceremonies. The US military wanted to determine if mescaline intake was a problem for personnel readiness. Twenty thousand seventeen u... |
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The effects of a humanized recombinant anti-cocaine monoclonal antibody on the disposition of cocaethylene in mice.
Int. Immunopharmacol. 23(2) , 387-90, (2015) The chimeric human/mouse anti-cocaine monoclonal antibody (mAb) 2E2 and its further humanized variant h2E2 have been reported to sequester a significant portion of cocaine in plasma and decrease cocaine concentrations in the brain in mice and rats. However, m... |
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Application of direct-infusion ESI-MS/MS for toxicological screening.
Bioanalysis 6(15) , 2043-55, (2014) Direct-infusion ESI-MS/MS is a powerful approach for the identification of substances in complex mixtures. The aim of this work was to investigate its applicability to the toxicological screening of blood samples. A simple protein precipitation was used, foll... |
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Simple method for determination of cocaine and main metabolites in urine by CE coupled to MS.
Electrophoresis 30(12) , 2238-44, (2009) In this work, a simple method for the simultaneous determination of cocaine (COC) and five COC metabolites (benzoylecgonine, cocaethylene (CET), anhydroecgonine, anhydroecgonine methyl ester and ecgonine methyl ester) in human urine using CE coupled to MS via... |
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The ability of bacterial cocaine esterase to hydrolyze cocaine metabolites and their simultaneous quantification using high-performance liquid chromatography-tandem mass spectrometry.
Mol. Pharmacol. 80(6) , 1119-27, (2011) Cocaine toxicity is a widespread problem in the United States, responsible for more than 500,000 emergency department visits a year. There is currently no U.S. Food and Drug Administration-approved pharmacotherapy to directly treat cocaine toxicity. To this e... |
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Hair analysis for cocaine continues to be a valuable tool in forensic and clinical toxicology.
J. Anal. Toxicol. 34(6) , 354-5; author reply 355-6, (2010)
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Single hair cocaine consumption monitoring by mass spectrometric imaging.
Anal. Chem. 83(11) , 4266-72, (2011) Matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) was used to image the distribution of cocaine and its metabolites in intact single hair samples from chronic users down to a concentration of 5 ng/mg. Acquisitions were perform... |
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Cocaine analytes in human hair: evaluation of concentration ratios in different cocaine sources, drug-user populations and surface-contaminated specimens.
J. Anal. Toxicol. 36(6) , 390-8, (2012) Hair specimens were analyzed for cocaine (COC), benzoylecgonine (BE), cocaethylene (CE) and norcocaine (NCOC) by liquid chromatography-tandem mass spectrometry. Drug-free hair was contaminated in vitro with COC from different sources with varied COC analyte c... |