6-Methoxycarbonyl-3-cyclohexene-1-carboxylicacid

6-Methoxycarbonyl-3-cyclohexene-1-carboxylicacid Structure
6-Methoxycarbonyl-3-cyclohexene-1-carboxylicacid structure
Common Name 6-Methoxycarbonyl-3-cyclohexene-1-carboxylicacid
CAS Number 88335-93-7 Molecular Weight 184.189
Density 1.2±0.1 g/cm3 Boiling Point 306.5±42.0 °C at 760 mmHg
Molecular Formula C9H12O4 Melting Point 65-67ºC
MSDS USA Flash Point 121.3±21.4 °C

Chiral synthon obtained with pig liver esterase: introduction of chiral centers into cyclohexene skeleton.

Chem. Pharm. Bull. 38(2) , 350-4, (1990)

A versatile chiral synthon, (1R,6S)-6-methoxycarbonyl-3-cyclohexene-1-carboxylic acid, was obtained by an enantioselective hydrolysis of the corresponding meso diester with pig liver esterase. This enzymatic hydrolysis can easily be carried out on a multi-hun...

N. Tamura et al.

Tetrahedron Lett. 27 , 3749, (1986)

W. Boland et al.

Helv. Chim. Acta 68 , 2062, (1985)

S. Kobayashi et al.

Tetrahedron Lett. 25 , 2557, (1984)

G.S. Hamilton et al.

J. Org. Chem. 58 , 7263, (1993)