5-Bromoindole
5-Bromoindole structure
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Common Name | 5-Bromoindole | ||
|---|---|---|---|---|
| CAS Number | 10075-50-0 | Molecular Weight | 196.044 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 316.9±15.0 °C at 760 mmHg | |
| Molecular Formula | C8H6BrN | Melting Point | 90-92 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 145.5±20.4 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Identification of novel CYP2A6 inhibitors by virtual screening
Bioorg. Med. Chem. 19 , 7186-93, (2011) The human CYP2A6 enzyme metabolises several xenobiotics including nicotine, the addictive component in tobacco. Reduced activity of CYP2A6, either for genetic reasons or by administering inhibitors of CYP2A6, reduces tobacco smoking. The aim was to design nov... |
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Rational design of novel CYP2A6 inhibitors.
Bioorg. Med. Chem. 22(23) , 6655-64, (2015) Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by evaluating CYP2A6 inhibitory effect of novel formyl, alkyl a... |
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Untargeted Screening and Distribution of Organo-Bromine Compounds in Sediments of Lake Michigan.
Environ. Sci. Technol. 50 , 321-30, (2016) Previously unreported natural and synthetic organo-bromine compounds (NSOBCs) have been found to contribute more than 99% of total organic bromine (TOB) in environmental matrices. We recently developed a novel untargeted method (data-independent precursor iso... |