4-Methoxyindole

4-Methoxyindole Structure
4-Methoxyindole structure
Common Name 4-Methoxyindole
CAS Number 4837-90-5 Molecular Weight 147.17
Density 1.2±0.1 g/cm3 Boiling Point 306.9±0.0 °C at 760 mmHg
Molecular Formula C9H9NO Melting Point 69-70 °C(lit.)
MSDS Chinese USA Flash Point 109.2±10.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Pharmacokinetics and pharmacodynamics of 3,3'-diindolylmethane (DIM) in regulating gene expression of phase II drug metabolizing enzymes.

J. Pharmacokinet. Pharmacodyn. 42 , 401-8, (2015)

3,3'-Diindolylmethane (DIM) has been investigated as a potential anti-cancer chemopreventive agent in many preclinical and clinical studies. In this study, we sought to characterize the pharmacokinetics of DIM and to build a pharmacokinetic (PK) and pharmacod...

Intranasal delivery of liposomal indole-3-carbinol improves its pulmonary bioavailability.

Int. J. Pharm. 477(1-2) , 96-101, (2014)

Indole-3-carbinol (I3C), a constituent of commonly consumed Brassica vegetables, has been shown to have anticancer effects in a variety of preclinical models of lung cancer. However, it has shown only limited efficacy in clinical trials, likely due to its poo...

HPLC and solubility study of the interaction between pindolol and cyclodextrins.

J. Pharm. Biomed. Anal. 37(3) , 487-92, (2005)

The complexation with beta-cyclodextrin (beta-CD) has been investigated using reversed-phase liquid chromatography. The compounds tested have been pindolol and, for comparison purposes, indole and 4-methoxyindole. The retention behaviour has been analysed on ...