6-Hydroxyindole

6-Hydroxyindole Structure
6-Hydroxyindole structure
Common Name 6-Hydroxyindole
CAS Number 2380-86-1 Molecular Weight 133.15
Density 1.3±0.1 g/cm3 Boiling Point 343.2±15.0 °C at 760 mmHg
Molecular Formula C8H7NO Melting Point 124-130 °C
MSDS Chinese USA Flash Point 161.4±20.4 °C
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger

Determination of selected synthetic cannabinoids and their metabolites by micellar electrokinetic chromatography--mass spectrometry employing perfluoroheptanoic acid-based micellar phase.

Talanta 150 , 568-76, (2016)

Perfluoroheptanoic acid was employed as a volatile micellar phase in background electrolyte for micellar electrokinetic chromatography-tandem mass spectrometry separation and determination of 15 selected naphthoyl- and phenylacetylindole- synthetic cannabinoi...

Inhibitory effect of hydroxyindoles and their analogues on human melanoma tyrosinase.

Z. Naturforsch., C, J. Biosci. 65 , 49-54, (2010)

A recent study showed that N-acylserotonin derivatives have strong inhibitory activity against tyrosinase. To clarify the role of the 5-hydroxy group in the indole ring, 2-, 4-, 5-, 6-, and 7-hydroxyindole and 11 related compounds such as 5-hydroxyindan and 6...

Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent.

PLoS ONE 8(1) , e54767, (2013)

Human UDP-glucuronosyltransferases (UGTs) are important enzymes in metabolic elimination of endo- and xenobiotics. It was recently shown that addition of fatty acid free bovine serum albumin (BSA) significantly enhances in vitro activities of UGTs, a limiting...

Enterohemorrhagic Escherichia coli biofilms are inhibited by 7-hydroxyindole and stimulated by isatin.

Appl. Environ. Microbiol. 73(13) , 4100-9, (2007)

Since indole is present at up to 500 microM in the stationary phase and is an interspecies biofilm signal (J. Lee, A. Jayaraman, and T. K. Wood, BMC Microbiol. 7:42, 2007), we investigated hydroxyindoles as biofilm signals and found them also to be nontoxic i...