1,4-Cyclohexanediol
1,4-Cyclohexanediol structure
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Common Name | 1,4-Cyclohexanediol | ||
|---|---|---|---|---|
| CAS Number | 556-48-9 | Molecular Weight | 116.158 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 252.4±0.0 °C at 760 mmHg | |
| Molecular Formula | C6H12O2 | Melting Point | 98-100ºC | |
| MSDS | Chinese USA | Flash Point | 65.6±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Core-shell polymer nanoparticles for prevention of GSH drug detoxification and cisplatin delivery to breast cancer cells.
Nanoscale 7 , 17964-79, (2015) Platinum drug delivery against the detoxification of cytoplasmic thiols is urgently required for achieving efficacy in breast cancer treatment that is over expressed by glutathione (GSH, thiol-oligopeptide). GSH-resistant polymer-cisplatin core-shell nanopart... |
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Biological monitoring of occupational exposure to cyclohexane by urinary 1,2- and 1,4-cyclohexanediol determination.
Int. Arch. Occup. Environ. Health 72(2) , 115-20, (1999) This article reports the results obtained with the biological and environmental monitoring of occupational exposure to cyclohexane using 1,2-cyclohexanediol (1,2-DIOL) and 1,4-DIOL in urine. The kinetic profile of 1,2-DIOL in urine suggested by a physiologica... |
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Oxidation of cyclohexanediol derivatives with 12-tungstophosphoric acid-hydrogen peroxide system.
J. Oleo Sci. 58(6) , 323-8, (2009) Oxidation of cyclohexanediol derivatives with 12-tungstophospholic acid-hydrogen peroxide system was investigated focusing on a reaction mechanism in the preparation of dicarboxylic acids from olefin because oxidative cleavage of vicinal diols would be a rate... |
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Urinary excretion of cyclohexanediol, a metabolite of the solvent cyclohexanone, by infants in a special care unit.
Clin. Chem. 36(6) , 870-4, (1990) Using gas chromatography-mass spectrometry, we investigated the urinary excretion of organic acids of 278 newborn babies in a special care unit to obtain reference data and monitor metabolism. In 101 of 584 urine samples analyzed, we found isomers of cyclohex... |
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1,2- and 1,4-Cyclohexanediol: major urinary metabolites and biomarkers of exposure to cyclohexane, cyclohexanone, and cyclohexanol in humans.
Int. Arch. Occup. Environ. Health 71(8) , 560-5, (1998) The metabolism and toxicokinetics of cyclohexane (CH) and cyclohexanol (CH-ol), important solvents and chemical intermediates, were studied in volunteers after 8-h periods of inhalation exposure at concentrations of 1010 and 236 mg m(-3), respectively (occupa... |
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Synergistic effect of 1,4-cyclohexanediol and 1,2-hexanediol on percutaneous absorption and penetration of metronidazole.
Int. J. Pharm. 415(1-2) , 169-74, (2011) The objective of this study was to investigate the percutaneous absorption of metronidazole (MTZ) in the topical formulations containing a combination of 1,4-cyclohexanediol and 1,2-hexanediol. Six formulations were studied in an in vitro hairless mouse skin ... |
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Diol-linked microporous networks of cubic siloxane cages.
Chemistry 19(5) , 1700-5, (2013) A new class of inorganic-organic hybrid porous materials has been synthesized by a reaction between octa(hydridosilsesquioxane) (H(8)Si(8)O(12)), which has a double-four-ring (D4R) structure, and various diols, such as 1,3-propanediol (PD), 1,4-cyclohexanedio... |
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Effect of 1,4-cyclohexanediol on percutaneous absorption and penetration of azelaic acid.
Int. J. Pharm. 387(1-2) , 167-71, (2010) The objective of this study is to investigate the effect of 1,4-cyclohexanediol as a retardant on the percutaneous absorption and penetration of azelaic acid. Hairless rat skin was mounted on Franz diffusion cells and treated with topical formulations contain... |
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A gene linB2 responsible for the conversion of beta-HCH and 2,3,4,5,6-pentachlorocyclohexanol in Sphingomonas sp. BHC-A.
Appl. Microbiol. Biotechnol. 73(5) , 1097-105, (2007) Commercial formulations of hexachlorocyclohexane (HCH) consist of a mixture of four isomers: alpha, beta, gamma, and delta. All four isomers are toxic and recalcitrant pollutants. beta-HCH is more problematic due to its longer persistence in the environment. ... |
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Hydrogen-bond patterns and the structures of 1,4-cyclohexanediol: 2:1 cis:trans-1,4-cyclohexanediol.
Acta Crystallogr. B 64(Pt 5) , 583-8, (2008) The structure of a co-crystal with both trans and cis isomers of 1,4-cyclohexanediol (1,4-CHD) is reported. The intermolecular hydrogen-bond patterns are described and compared with those of the all trans structure, using the graph-set model. A second crystal... |