meglumine
meglumine structure
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Common Name | meglumine | ||
|---|---|---|---|---|
| CAS Number | 6284-40-8 | Molecular Weight | 195.214 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 490.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C7H17NO5 | Melting Point | 128-132ºC | |
| MSDS | Chinese USA | Flash Point | 251.6±19.3 °C | |
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A-803467, a tetrodotoxin-resistant sodium channel blocker, modulates ABCG2-mediated MDR in vitro and in vivo.
Oncotarget 6 , 39276-91, (2015) ATP-binding cassette subfamily G member 2 (ABCG2) is a member of the ABC transporter superfamily proteins, which has been implicated in the development of multidrug resistance (MDR) in cancer, apart from its physiological role to remove toxic substances out o... |
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ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) are not primary resistance factors for cabazitaxel.
Chin. J. Cancer 34 , 115-20, (2015) ATP-binding cassette subfamily B member 1 (ABCB1) and subfamily C member 10 (ABCC10) proteins are efflux transporters that couple the energy derived from ATP hydrolysis to the translocation of toxic substances and chemotherapeutic drugs out of cells. Cabazita... |
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A novel surface-confined glucaminium-based ionic liquid stationary phase for hydrophilic interaction/anion-exchange mixed-mode chromatography.
J. Chromatogr. A. 1360 , 240-7, (2014) Glucaminium-based ionic liquids are a new class of recently developed ionic liquids and prepared by functionalizing the amine group of N-methyl-d-glucamine, which renders them good hydrophilicity due to the presence of the glucose structure and charged quater... |
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Caspase-dependent cell death-associated release of nucleosome and damage-associated molecular patterns.
Cell Death Dis. 5 , e1494, (2014) Apoptosis, which is anti-inflammatory, and necrosis, which is pro-inflammatory, represent the extremes of the cell death spectrum. Cell death is complex and both apoptosis and necrosis can be observed in the same cells or tissues. Here, we introduce a novel c... |
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Coformer screening using thermal analysis based on binary phase diagrams.
Pharm. Res. 31(8) , 1946-57, (2014) The advent of cocrystals has demonstrated a growing need for efficient and comprehensive coformer screening in search of better development forms, including salt forms. Here, we investigated a coformer screening system for salts and cocrystals based on binary... |
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Cyclosporine A reduces microvascular obstruction and preserves left ventricular function deterioration following myocardial ischemia and reperfusion.
Basic Res. Cardiol. 110(2) , 18, (2015) Postconditioning and cyclosporine A prevent mitochondrial permeability transition pore opening providing cardioprotection during ischemia/reperfusion. Whether microvascular obstruction is affected by these interventions is largely unknown. Pigs subjected to c... |
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Anionic Lipids Modulate the Activity of the Aquaglyceroporin GlpF.
Biophys. J. 109 , 722-31, (2015) The structure and composition of a biological membrane can severely influence the activity of membrane-embedded proteins. Here, we show that the E. coli aquaglyceroporin GlpF has only little activity in lipid bilayers formed from native E. coli lipids. Thus, ... |
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Synthesis and characterization of bismuth(III) and antimony(V) porphyrins: high antileishmanial activity against antimony-resistant parasite.
J. Biol. Inorg. Chem. 20 , 771-9, (2015) Two bismuth(III) porphyrins-5,10,15,20-tetrakis(phenyl)porphyrinatobismuth(III) nitrate, [Bi(III)(TPP)]NO3, and the unprecedent 5,10,15,20-tetrakis(4-carbomethoxyphenyl)porphyrinatobismuth(III) nitrate, [Bi(III)(T4CMPP)]NO3, and two unprecedented antimony(V) ... |
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The role of action potentials in determining neuron-type-specific responses to nitric oxide.
Dev. Neurobiol. 75(5) , 435-51, (2015) The electrical activity in developing and mature neurons determines the intracellular calcium concentration ([Ca(2+)]i), which in turn is translated into biochemical activities through various signaling cascades. Electrical activity is under control of neurom... |
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In vitro drug susceptibility of Leishmania infantum isolated from humans and dogs.
Exp. Parasitol. 135(1) , 36-41, (2013) Visceral leishmaniasis (VL) caused by parasites of Leishmania donovani complex is a severe human disease which often leads to death if left untreated. Domestic dogs are the main reservoir hosts for zoonotic human visceral infection caused by Leishmania infant... |