Salicylhydrazide
Salicylhydrazide structure
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Common Name | Salicylhydrazide | ||
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| CAS Number | 936-02-7 | Molecular Weight | 152.15100 | |
| Density | 1.318g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C7H8N2O2 | Melting Point | 147-150 °C(lit.) | |
| MSDS | N/A | Flash Point | N/A | |
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Synthesis, Characterization, and Anticancer Activity of New Metal Complexes Derived from 2-Hydroxy-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide.
Bioinorg. Chem. Appl. 2015 , 126023, (2015) Novel metal(II) complexes derived from 2-hydroxy-N'-((Z)-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide ligand (H2L) were synthesized and characterized by elemental and thermal analyses (DTA and TGA), IR, UV-VIS, (1)H-NMR, ESR and mass spectroscopy, ma... |
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Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors.
Br. J. Pharmacol. 142 , 97-106 , (2004) 1. A high-throughput assay utilizing the voltage/ion probe reader (VIPR) technology identified salicylidene salicylhydrazide (SCS) as being a potent selective inhibitor of alpha2beta1gamma1 GABA(A) receptors with a maximum inhibition of 56+/-5% and an IC(50) ... |
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Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.
Bioorg. Med. Chem. Lett. 17(23) , 6472-5, (2007) The previously discovered salicylhydrazide class of compounds displayed potent HIV-1 integrase (IN) inhibitory activity. The development of this class of compounds as antiretroviral agents was halted due to cytotoxicity in the nanomolar to sub-micromolar rang... |
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Elucidation of the molecular mechanisms of a salicylhydrazide class of compounds by proteomic analysis.
Curr. Cancer Drug Targets 9(2) , 189-201, (2009) Previously, we described a series of salicylhydrazide compounds with potent anti-cancer activities against a panel of human cancer cell lines derived from different origins. Preclinical evaluation showing efficacy both in vitro and in vivo in human cancer mod... |
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The emitting species formed by the oxidation of hydrazides with hypohalites or N-halosuccinimides.
Luminescence 19(4) , 205-8, (2004) The chemiluminescence accompanying the oxidation of salicylic hydrazide (2-hydroxybenzoic acid hydrazide) with hypochlorite, hypobromite, N-chlorosuccinimide, N-bromosuccinimide or hydrogen peroxide with cobalt(II) matched the photoluminescence emission of sa... |