Atractylenolide III
Atractylenolide III structure
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Common Name | Atractylenolide III | ||
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| CAS Number | 73030-71-4 | Molecular Weight | 248.318 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 424.6±45.0 °C at 760 mmHg | |
| Molecular Formula | C15H20O3 | Melting Point | 200-201ºC | |
| MSDS | USA | Flash Point | 181.1±21.5 °C | |
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Sesquiterpenoids from Atractylodes macrocephala act as farnesoid X receptor and progesterone receptor modulators.
Bioorg. Med. Chem. Lett. 22 , 2326-2329, (2012) Two sesquiterpenoids, atractylenolide II and III, were isolated and identified from Atractylodes macrocephala (Asteraceae) to be subsequently evaluated for their activity against farnesoid X receptor (FXR) and progesterone receptor (PR) by transient transfect... |
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Targeting of the Sonic Hedgehog pathway by atractylenolides promotes chondrogenic differentiation of mesenchymal stem cells.
Biol. Pharm. Bull. 35 , 1328-1335, (2012) Molecules that enhance chondrogenic differentiation in mesenchymal stem cells (MSCs) were identified and isolated using an in vitro Gli reporter gene assay in MSCs incorporating a Sonic Hedgehog (Shh) target. Atractylenolide III, which promoted Gli1-mediated ... |
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Pharmacokinetic Profiles of Active Ingredients and Its Metabolites Derived from Rikkunshito, a Ghrelin Enhancer, in Healthy Japanese Volunteers: A Cross-Over, Randomized Study.
PLoS ONE 10 , e0133159, (2015) Rikkunshito, a traditional Japanese (Kampo) medicine, has been used to treat upper gastrointestinal disorders such as functional dyspepsia and gastroesophageal reflux. This study investigated the exposure and pharmacokinetics of the ingredients of rikkunshito... |
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Stereospecific analytical method development and preliminary in vivo pharmacokinetic characterization of pinostrobin in the rat. Sayre CL, Zhang Y, Martinez SE, et al.
Biomed. Chromatogr. , (2012)
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