Salidroside
Salidroside structure
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Common Name | Salidroside | ||
|---|---|---|---|---|
| CAS Number | 10338-51-9 | Molecular Weight | 300.304 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 549.5±50.0 °C at 760 mmHg | |
| Molecular Formula | C14H20O7 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 286.2±30.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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A pH-responsive nano-carrier with mesoporous silica nanoparticles cores and poly(acrylic acid) shell-layers: fabrication, characterization and properties for controlled release of salidroside.
Int. J. Pharm. 446(1-2) , 153-9, (2013) A novel pH-responsive nano-carrier MSNs-PAA, possessing mesoporous silica nanoparticles (MSNs) cores and poly(acrylic acid) (PAA) shell-layers, was developed for controlled release of salidroside. The vinyl double bonds modified MSNs were synthesized by using... |
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Inhibitory effects of salidroside and paeonol on tyrosinase activity and melanin synthesis in mouse B16F10 melanoma cells and ultraviolet B-induced pigmentation in guinea pig skin.
Phytomedicine 20(12) , 1082-7, (2013) Salidroside, the major active component of Rhodiola rosea, a herb with antioxidant, free radical scavenging and tyrosinase inhibitory effects, has been recently reported in protecting the kerationcytes from the UV radiation, suggesting the potential of this c... |
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Salidroside protects retinal endothelial cells against hydrogen peroxide-induced injury via modulating oxidative status and apoptosis.
Biosci. Biotechnol. Biochem. 79 , 1406-13, (2015) Oxidative stress can cause injury in retinal endothelial cells. Salidroside is a strong antioxidative and cytoprotective supplement in Chinese traditional medicine. In this study, we investigated the effects of salidroside on H2O2-induced primary retinal endo... |
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Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway.
Br. J. Pharmacol. 172 , 3284-301, (2015) Recent reports have suggested that salidroside could protect cardiomyocytes from oxidative injury and stimulate glucose uptake in skeletal muscle cells by activating AMP-activated protein kinase (AMPK). The aim of this study was to evaluate the therapeutic ef... |
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Salidroside protects against premature senescence induced by ultraviolet B irradiation in human dermal fibroblasts.
Int. J. Cosmet. Sci. 37 , 321-8, (2015) Salidroside, the predominant component of a Chinese herbal medicine, Rhodiola rosea L., becomes an attractive bio-agent due to its multifunction. Although it is well proposed that this herbal medicine may have photoprotective effect according to the folk hear... |
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Salidroside inhibits the growth of human breast cancer in vitro and in vivo.
Oncol. Rep. 33(5) , 2553-60, (2015) Salidroside has been identified as one of the most potent compounds isolated from the plant Rhodiola rosea, and was found to have several important biological properties, including antioxidant and anti-inflammatory activity; however, its anticancer effects ar... |
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The cardiovascular effects of salidroside in the Goto-Kakizaki diabetic rat model.
J. Physiol. Pharmacol. 66 , 249-57, (2015) Many factors, including hyperglycemia, hypertension, obesity, dyslipidemia, and a sedentary lifestyle, contribute to a high prevalence of cardiovascular disease. Specific vascular impairment treatments in the context of diabetes and vascular risk need to be i... |
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Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data.
Phytomedicine 21(11) , 1325-48, (2014) The aim of this study was to identify the targets (genes, interactive signaling pathways, and molecular networks) of Rhodiola rosea extract in isolated neuroglia cells and to predict the effects of Rhodiola extract on cellular functions and diseases. In addit... |
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Salidroside attenuates chronic hypoxia-induced pulmonary hypertension via adenosine A2a receptor related mitochondria-dependent apoptosis pathway.
J. Mol. Cell. Cardiol. 82 , 153-66, (2015) Pulmonary arterial hypertension (PAH) is characterized by pulmonary arterial remodeling mainly due to excess cellular proliferation and apoptosis resistance of pulmonary arterial smooth muscle cells (PASMCs). Salidroside, an active ingredient isolated from Rh... |
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Salidroside-Mediated Neuroprotection is Associated with Induction of Early Growth Response Genes (Egrs) Across a Wide Therapeutic Window.
Neurotox. Res. 28 , 108-21, (2015) Salidroside exhibits anti-inflammatory, anti-oxidative, and anti-apoptotic properties. To identify whether salidroside might be a candidate for treating ischemic stroke, we investigated the effects of salidroside or vehicle, given daily for 6 days, after midd... |