(R)-5,5-Dimethyl-1,3-thiazolidine-4-carboxylic acid

(R)-5,5-Dimethyl-1,3-thiazolidine-4-carboxylic acid Structure
(R)-5,5-Dimethyl-1,3-thiazolidine-4-carboxylic acid structure
Common Name (R)-5,5-Dimethyl-1,3-thiazolidine-4-carboxylic acid
CAS Number 72778-00-8 Molecular Weight 161.22200
Density N/A Boiling Point N/A
Molecular Formula C6H11NO2S Melting Point 206ºC dec.
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Identification of HERC5 and its potential role in NSCLC progression.

Int. J. Cancer 136(10) , 2264-72, (2015)

For better lung cancer diagnosis and therapy, early detection markers of tumor dissemination are urgently needed, as most lung cancers do not show symptoms until extensive metastasis formation has already taken place. Our previous studies showed that in non-s...

Simultaneous Nanoscale Surface Charge and Topographical Mapping.

ACS Nano 9 , 7266-76, (2015)

Nanopipettes are playing an increasingly prominent role in nanoscience, for sizing, sequencing, delivery, detection, and mapping interfacial properties. Herein, the question of how to best resolve topography and surface charge effects when using a nanopipette...

Enhanced NMDA receptor-mediated modulation of excitatory neurotransmission in the dorsal vagal complex of streptozotocin-treated, chronically hyperglycemic mice.

PLoS ONE 10(3) , e0121022, (2015)

A variety of metabolic disorders, including complications experienced by diabetic patients, have been linked to altered neural activity in the dorsal vagal complex. This study tested the hypothesis that augmentation of N-Methyl-D-Aspartate (NMDA) receptor-med...

Characterization of single disseminated prostate cancer cells reveals tumor cell heterogeneity and identifies dormancy associated pathways.

Oncotarget 5(20) , 9939-51, (2014)

Cancer dormancy refers to the prolonged clinical disease-free time between removal of the primary tumor and recurrence, which is common in prostate cancer (PCa), breast cancer, esophageal cancer, and other cancers. PCa disseminated tumor cells (DTC) are detec...

Inhibition of miR-146b expression increases radioiodine-sensitivity in poorly differential thyroid carcinoma via positively regulating NIS expression.

Biochem. Biophys. Res. Commun. 462 , 314-21, (2015)

Dedifferentiated thyroid carcinoma (DTC) with the loss of radioiodine uptake (RAIU) is often observed in clinical practice under radioiodine therapy, indicating the challenge for poor prognosis. MicroRNA (miRNA) has emerged as a promising therapeutic target i...

Maintenance of Clonogenic KIT(+) Human Colon Tumor Cells Requires Secretion of Stem Cell Factor by Differentiated Tumor Cells.

Gastroenterology 149 , 692-704, (2015)

Colon tumors contain a fraction of undifferentiated stem cell-like cancer cells with high tumorigenic potential. Little is known about the signals that maintain these stem-like cells. We investigated whether differentiated tumor cells provide support.We estab...

Detection and prevalence of disseminated tumor cells from the bone marrow of early stage male breast cancer patients.

Breast Cancer Res. Treat. 152 , 51-5, (2015)

Male breast cancer (mBC) is a rare entity. As detection of disseminated tumor cells (DTCs) in the bone marrow of females with early stage breast cancer is a promising prognostic marker, we aimed to determine the prevalence and prognostic value of DTCs in mBC....

Clinical management and outcomes in patients with hyperfunctioning distant metastases from differentiated thyroid cancer after total thyroidectomy and radioactive iodine therapy.

Thyroid 25(2) , 229-37, (2015)

Hyperfunctioning distant metastasis (HFDM) from differentiated thyroid cancer (DTC) is a rare entity. This study aimed to assess the outcomes of DTC patients presenting with HFDM after total thyroidectomy and radioactive iodine therapy.A total of 5367 DTC pat...

Disease-specific direct-to-consumer advertising of pharmaceuticals: An examination of endorser type and gender effects on consumers' attitudes and behaviors.

Res. Social Adm. Pharm. 11 , 891-900, (2015)

Direct-to-consumer (DTC) advertising is still a controversial topic for pharmaceutical manufacturers' and researchers, and while numerous studies have examined the DTC phenomenon, little research has examined the effect of gender, particularly gender of the e...

Retrospective imaging study on the diagnosis of pathological false positive iodine-131 scans in patients with thyroid cancer.

Exp. Ther. Med. 10 , 1995-2001, (2015)

Iodine-131 (I-131) therapy and post-therapy I-131 scanning are essential in the management of differentiated thyroid cancer (DTC). However, pathological false positive I-131 scans can lead to misdiagnosis and inappropriate I-131 treatment. This retrospective ...