n-propylmaleimide

n-propylmaleimide Structure
n-propylmaleimide structure
Common Name n-propylmaleimide
CAS Number 21746-40-7 Molecular Weight 139.15200
Density 1.073 Boiling Point 97ºC18 mm Hg(lit.)
Molecular Formula C7H9NO2 Melting Point 24-26ºC
MSDS Chinese USA Flash Point 95ºC
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Warning

Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds.

Bioorg. Med. Chem. 19 , 2823-34, (2011)

The synthesis, in vitro evaluation and SAR studies of 67 maleimides and derivatives acting as antifungal agents are reported. A detailed SAR study supported by theoretical calculations led us to determine that: an intact maleimido ring appears to be necessary...