1,3-Dimethyl-2-imidazolidinone
1,3-Dimethyl-2-imidazolidinone structure
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Common Name | 1,3-Dimethyl-2-imidazolidinone | ||
|---|---|---|---|---|
| CAS Number | 80-73-9 | Molecular Weight | 114.146 | |
| Density | 1.044 | Boiling Point | 225.5 ºC | |
| Molecular Formula | C5H10N2O | Melting Point | 8.2 °C | |
| MSDS | Chinese USA | Flash Point | 93 ºC | |
| Symbol |
GHS05, GHS07, GHS08 |
Signal Word | Danger | |
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A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.
PLoS Pathog. 11(2) , e1004621, (2015) Helicobacter pylori persistently colonizes the human stomach, with mixed roles in human health. The CagA protein, a key host-interaction factor, is translocated by a type IV secretion system into host epithelial cells, where its EPIYA tyrosine phosphorylation... |
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Minimal sequence requirements for oligodeoxyribonucleotides activating human TLR9.
J. Immunol. 194(8) , 3901-8, (2015) Synthetic oligodeoxyribonucleotides (ODNs) containing CpG (unmethylated deoxycytidylyl-deoxyguanosine dinucleotide) motifs activate endosomal TLR9. The nucleotide sequence, length, and dimerization properties of ODNs modulate their activation of TLR9. We perf... |
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PI3K signalling is required for a TGFβ-induced epithelial-mesenchymal-like transition (EMT-like) in human melanoma cells.
Exp. Dermatol. 24(1) , 22-8, (2015) Epithelial to mesenchymal transition (EMT) is a programme defined in epithelial cells and recognized as playing a critical role in cancer progression. Although melanoma is not a cancer of epithelial cells, hallmarks of EMT have been described to play a critic... |
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Anionic nanoparticles based on Span 80 as low-cost, simple and efficient non-viral gene-transfection systems.
Int. J. Pharm. 476(1-2) , 23-30, (2015) The existing strategies in the design of non-viral vectors for gene therapy are primarily conceived for cationic systems. However, the safety concerns associated with the use of positively charged systems for nucleic acid delivery and several reports regardin... |
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Plasma-assisted hydrophilization of cochlear implant electrode array surfaces enables adhesion of neurotrophin-secreting cells.
ORL J. Otorhinolaryngol. Relat. Spec. 76(5) , 257-65, (2015) To evaluate plasma treatment for enhancing the biocompatibility of cochlear implant (CI) silicone surfaces, thus allowing colonization with human adipose-derived stem cells (hASCs) that are known to provide neurotrophic support.Silicone samples and CI electro... |
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Flavonoid-modified surfaces: multifunctional bioactive biomaterials with osteopromotive, anti-inflammatory, and anti-fibrotic potential.
Adv. Healthc. Mater. 4(4) , 540-9, (2015) Flavonoids are small polyphenolic molecules of natural origin with antioxidant, anti-inflammatory, and antibacterial properties. Here, a bioactive surface based on the covalent immobilization of flavonoids taxifolin and quercitrin on titanium substrates is pr... |
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CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction.
Cancer Res. 74(23) , 6878-89, (2014) CD98hc (SLC3A2) is the heavy chain component of the dimeric transmembrane glycoprotein CD98, which comprises the large neutral amino acid transporter LAT1 (SLC7A5) in cells. Overexpression of CD98hc occurs widely in cancer cells and is associated with poor pr... |
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Regulation of ICAM-1 in cells of the monocyte/macrophage system in microgravity.
Biomed Res. Int. 2015 , 538786, (2015) Cells of the immune system are highly sensitive to altered gravity, and the monocyte as well as the macrophage function is proven to be impaired under microgravity conditions. In our study, we investigated the surface expression of ICAM-1 protein and expressi... |
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A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis.
J. Antimicrob. Chemother. 70(2) , 510-7, (2015) To optimize the Trypanosoma brucei brucei GVR35 VSL-2 bioluminescent strain as an innovative drug evaluation model for late-stage human African trypanosomiasis.An IVIS® Lumina II imaging system was used to detect bioluminescent T. b. brucei GVR35 parasites in... |
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Local and systemic regulation of plant root system architecture and symbiotic nodulation by a receptor-like kinase.
PLoS Genet. 10(12) , e1004891, (2014) In plants, root system architecture is determined by the activity of root apical meristems, which control the root growth rate, and by the formation of lateral roots. In legumes, an additional root lateral organ can develop: the symbiotic nitrogen-fixing nodu... |