trimellitic anhydride

trimellitic anhydride Structure
trimellitic anhydride structure
Common Name trimellitic anhydride
CAS Number 552-30-7 Molecular Weight 192.125
Density 1.7±0.1 g/cm3 Boiling Point 470.6±28.0 °C at 760 mmHg
Molecular Formula C9H4O5 Melting Point 163-166 °C(lit.)
MSDS Chinese USA Flash Point 201.3±17.5 °C
Symbol GHS05 GHS07 GHS08
GHS05, GHS07, GHS08
Signal Word Danger

Skin sensitization induced Langerhans' cell mobilization: variable requirements for tumour necrosis factor-α.

Immunology 144(1) , 139-48, (2015)

Upon antigen/allergen recognition, epidermal Langerhans' cells (LC) are mobilized and migrate to the local lymph node where they play a major role in initiating or regulating immune responses. It had been proposed that all chemical allergens induce LC migrati...

Synthesis and properties of optically active nanostructured polymers bearing amino acid moieties by direct polycondensation of 4,4'-thiobis(2-tert-butyl-5-methylphenol) with chiral diacids.

Amino Acids 42(6) , 2187-94, (2012)

Four derivatives of N-trimellitylimido-L-amino acid (4a-4d) were prepared by the reaction of trimellitic anhydride (1) with the L-amino acids (2a-2d) in acetic acid as diacid monomers and were used with the aim to obtain a new family of amino acid based poly(...

A rare nail polish allergen: phthalic anhydride, trimellitic anhydride and glycols copolymer.

Contact Dermatitis 56(3) , 172-3, (2007)

Prior exposure to immunosuppressive organophosphorus or organochlorine compounds aggravates the T(H)1- and T(H)2-type allergy caused by topical sensitization to 2,4-dinitrochlorobenzene and trimellitic anhydride.

J. Immunotoxicol. 8(2) , 170-82, (2011)

Immunosuppressive environmental chemicals may increase the potency of allergens and thereby play a role in the development of allergic diseases. This study's primary objective was to examine the mechanisms behind the relationship between allergic diseases and...

Identification of contact and respiratory sensitizers according to IL-4 receptor α expression and IL-2 production.

Toxicol. Appl. Pharmacol. 260(2) , 95-104, (2012)

Identification of allergenic chemicals is an important occupational safety issue. While several methods exist to identify contact sensitizers, there is currently no validated model to predict the potential of chemicals to act as respiratory sensitizers. Previ...

Changes in asthma-like responses after extended removal from exposure to trimellitic anhydride in the Brown Norway rat model.

Clin. Exp. Allergy 39(11) , 1746-53, (2009)

Organic acid anhydride-induced occupational asthma is considered to be IgE-mediated. Airway and skin exposure are the two main routes of sensitization in the work place. Recently we developed an allergic asthmatic Brown Norway rat model sensitized by dermal e...

Is trimellitic anhydride skin testing a sufficient screening tool for selectively identifying TMA-exposed workers with TMA-specific serum IgE antibodies?

J. Occup. Environ. Med. 53(10) , 1122-7, (2011)

Trimellitic anhydride (TMA) can elicit specific IgE-mediated immune responses leading to asthma. This single-blinded study investigated the ability of TMA skin testing to identify workers with TMA-serum specific IgE antibodies.Forty TMA-exposed workers who we...

Preexposure to amorphous silica particles attenuates but also enhances allergic reactions in trimellitic anhydride-sensitized brown Norway rats.

Inhal. Toxicol. 20(10) , 935-48, (2008)

Irritant-induced inflammation of the airways may aggravate respiratory allergy induced by chemical respiratory allergens. Therefore, the effect of airway irritation by synthetic amorphous silica (SAS) on respiratory allergy to trimellitic anhydride (TMA) was ...

Molecular characterization of trimellitic anhydride-induced respiratory allergy in Brown Norway rats.

Toxicol. Pathol. 36(7) , 985-98, (2008)

To contribute to the hazard identification of low molecular weight (LMW) respiratory allergens, respiratory allergy induced by trimellitic anhydride (TMA) was characterized by whole genome analysis of lung tissue and blood proteomics in Brown Norway rats. Der...

Pre-exposure to sulfur dioxide attenuates most allergic reactions upon trimellitic anhydride challenge in sensitized Brown Norway rats.

Inhal. Toxicol. 22(3) , 179-91, (2010)

Irritant-induced inflammation of the airways may aggravate respiratory allergy induced by chemical respiratory allergens. Therefore, it was studied whether airway irritation by sulfur dioxide (SO(2)) would enhance respiratory allergic reactions to trimellitic...