4-Chloroacetanilide
4-Chloroacetanilide structure
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Common Name | 4-Chloroacetanilide | ||
|---|---|---|---|---|
| CAS Number | 539-03-7 | Molecular Weight | 169.608 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 335.0±25.0 °C at 760 mmHg | |
| Molecular Formula | C8H8ClNO | Melting Point | 176-178 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 156.4±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Development of EPA method 535 for the determination of chloroacetanilide and other acetamide herbicide degradates in drinking water by solid-phase extraction and liquid chromatography/tandem mass spectrometry.
J. AOAC Int. 89(1) , 201-9, (2006) U.S. Environmental Protection Agency (EPA) Method 535 has been developed in order to provide a method for the analysis of "Alachlor ESA and other acetanilide degradation products," which are listed on EPA's 1998 Drinking Water Contaminant Candidate List. Meth... |
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Toxicology laboratory analysis and human exposure to p-chloroaniline.
Clin. Toxicol. (Phila.) 47(2) , 132-6, (2009) p-Chloroaniline is more potent at producing methemoglobin than aniline in animal models. This case highlights the clinical presentation of an inhalation exposure to p-chloroaniline and associated laboratory analysis. An in-vitro study evaluating the metabolis... |
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Structural characterization and function determination of a nonspecific carboxylate esterase from the amidohydrolase superfamily with a promiscuous ability to hydrolyze methylphosphonate esters.
Biochemistry 53(21) , 3476-85, (2014) The uncharacterized protein Rsp3690 from Rhodobacter sphaeroides is a member of the amidohydrolase superfamily of enzymes. In this investigation the gene for Rsp3690 was expressed in Escherichia coli and purified to homogeneity, and the three-dimensional stru... |
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HPLC separation of acetaminophen and its impurities using a mixed-mode reversed-phase/cation exchange stationary phase.
J. Chromatogr. Sci. 50(4) , 335-42, (2012) Determination of acetaminophen and its main impurities: 4-nitrophenol, 4'-chloroacetanilide, as well as 4-aminophenol and its degradation products, p-benzoquinone and hydroquinone has been developed and validated by a new high-performance liquid chromatograph... |
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Generalized cytochrome P450-mediated oxidation and oxygenation reactions in aromatic substrates with activated N-H, O-H, C-H, or S-H substituents.
Xenobiotica 23(6) , 633-48, (1993) 1. The general mechanism of metabolic oxidation of substrates by cytochromes P450 (P450s) appears to consist of sequential one-electron oxidation steps rather than of a single concerted transfer of activated oxygen species from P450 to substrates. 2. In case ... |
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On-line reaction monitoring of lithiation of halogen substituted acetanilides via in situ calorimetry, ATR spectroscopy, and endoscopy.
Chimia 65(4) , 253-5, (2011) Lithiation of N-(4-chlorophenyl)-pivalamide (NCP) and two additional substituted acetanilides: 4-fluoroacetanilide (4-F) and 4-chloroacetanilide (4-Cl) has been monitored by means of calorimetry, on-line ATR-IR and UV/vis spectroscopy and endoscopy. The combi... |