Fluoroacetamide
Fluoroacetamide structure
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Common Name | Fluoroacetamide | ||
|---|---|---|---|---|
| CAS Number | 640-19-7 | Molecular Weight | 77.058 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 259.0±10.0 °C at 760 mmHg | |
| Molecular Formula | C2H4FNO | Melting Point | 106-108 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 110.4±19.0 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Simultaneous determination of two acute poisoning rodenticides tetramine and fluoroacetamide with a coupled column in poisoning cases.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 876(1) , 103-8, (2008) A coupled column system was developed for the simultaneous determination of both rodenticides fluoroacetamide and tetramine in this paper by gas chromatography/mass spectrometry (GC/MS). A short length of strong polar column (1.5 m of Innowax) was coupled to ... |
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Enzymatic defluorination and metabolism of fluoroacetate, fluoroacetamide, fluoroethanol, and (-)-erythro-fluorocitrate in rats and mice examined by 19F and 13C NMR.
Chem. Res. Toxicol. 2(6) , 429-35, (1989) Fluoroacetate administered intraperitoneally (ip) to rats and mice is defluorinated to give fluoride ion evident in urine and kidney by 19F NMR. The use of [2-13C]-, [1,2-13C]-, and [1,2-14C]fluoroacetate, prepared from isotopically labeled glycine, combined ... |
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[Determination of fluoroacetatamide and fluoroacetic acid by capillary gas chromatography].
Fa Yi Xue Za Zhi 13(2) , 77-8, inside back cover, (1997) A rapid qualitative and quantitative analysis of fluoroacetatamide and fluoroacetic acid in rodenticides by capillary gaschromatography was described in this paper. Isoamyl alcohol was used as the internal standard. The determination curves of fluoroacetatami... |
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Alpha-fluorovinyl Weinreb amides and alpha-fluoroenones from a common fluorinated building block.
J. Org. Chem. 74(10) , 3689-97, (2009) Synthesis and reactivity of N-methoxy-N-methyl-(1,3-benzothiazol-2-ylsulfonyl)fluoroacetamide, a building block for Julia olefination, is reported. This reagent undergoes condensation reactions with aldehydes and cyclic ketones to give alpha-fluorovinyl Weinr... |
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Insertion and replication of the Pseudomonas aeruginosa mutator phage D3112.
Mol. Gen. Genet. 192(3) , 416-23, (1983) D3112 is a temperate bacteriophage of P. aeruginosa with heterogeneous sequences at one extremity of the virion DNA molecule. Infection of strain PAOl with phage D3112 results in a 40- to 65-fold increase in the frequency of ami mutants resistant to fluoroace... |
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Fluoroacetamide resistance mutations in Chlamydomonas reinhardtii.
Arch. Microbiol. 148(1) , 8-13, (1987) Acetamide, a nitrogen and carbon source for Chlamydomonas reinhardtii, is hydrolyzed by acetamidase to ammonium and acetate. It also induces urea pathway activities. Fluoroacetamide (F-acetamide) is toxic to wildtype through conversion to F-citrate, a respira... |
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The role of fluoroacetate-specific dehalogenase and glutathione transferase in the metabolism of fluoroacetamide and 2,4-dinitrofluorobenzene.
Toxicol. Lett. 22(2) , 217-22, (1984) 2,4-Dinitrofluorobenzene (DNFB) reacts with glutathione to form a stable product similar to that formed with the model glutathione-S-transferase (GST) substrate, 1-chloro-2,4-dinitrobenzene (CDNB). DNFB is approx. 40 times als reactive as CDNB in this chemica... |
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Fast detection of fluoroacetamide in body fluid using gas chromatography-mass spectrometry after solid-phase microextraction.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 802(2) , 239-45, (2004) A novel method for fast determination of fluoroacetamide, a kind of organic fluorine pesticide, in blood and urine samples was developed with acetamide as an internal standard using gas chromatography/mass spectrometry (GC/MS) after solid-phase microextractio... |
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Electrophysiological study of infant and adult rats under acute intoxication with fluoroacetamide.
J. Appl. Toxicol. 27(6) , 538-50, (2007) A study was conducted of acute intoxication of infant and adult Wistar rats with fluoroacetamide (FAA), an inhibitor of oxidative metabolism. FAA was administered orally to adult rats at 1/2 LD(50) and subcutaneously to infant rats at LD(100) or 1/10 LD(50). ... |
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Isolation and phenotypic characterization of Pseudomonas aeruginosa pseudorevertants containing suppressors of the catabolite repression control-defective crc-10 allele.
FEMS Microbiol. Lett. 196(2) , 87-92, (2001) The amiE gene encodes an aliphatic amidase capable of converting fluoroacetamide to the toxic compound fluoroacetate and is one of many genes whose expression is subject to catabolite repression control in Pseudomonas aeruginosa. The protein product of the cr... |