Pemoline
Pemoline structure
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Common Name | Pemoline | ||
|---|---|---|---|---|
| CAS Number | 2152-34-3 | Molecular Weight | 176.17200 | |
| Density | 1.4g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H8N2O2 | Melting Point | 243ºC | |
| MSDS | Chinese USA | Flash Point | 143.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Fatigue in multiple sclerosis - a brief review.
J. Neurol. Sci. 323(1-2) , 9-15, (2012) Fatigue is the most common and debilitating symptom in multiple sclerosis (MS) and is believed to be distinctly different from fatigue seen in other chronic conditions. It can affect a patient's mood, sleep and have a detrimental effect on their quality of li... |
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Animal models of self-injurious behaviour: an overview.
Methods Mol. Biol. 829 , 65-84, (2012) Self-injurious behaviour is highly prevalent in neurodevelopmental disorders. Interestingly, it is not restricted to any individual diagnostic group. Rather, it is exhibited in various forms across patient groups with distinct genetic defects and classificati... |
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Pemoline induced acute choreoathetosis: case report and review of the literature.
J. Toxicol. Clin. Toxicol. 35(1) , 105-8, (1997) Pemoline is an oxazolidine derivative that is structurally different from amphetamines and used in the treatment of attention deficit disorder. Pemoline has not been commonly associated in the literature as a cause of acute movement disorders. The following c... |
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Pemoline (2-amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy.
J. Pharmacol. Exp. Ther. 324(1) , 214-23, (2008) Self-injury is a devastating, maladaptive behavior disorder that is common in developmental disabilities and is comorbid with numerous psychiatric disorders. Examples of self-injurious behavior (SIB) include head-banging, self-biting, and self-punching. The n... |
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Individual differences in vulnerability for self-injurious behavior: studies using an animal model.
Behav. Brain Res. 217(1) , 148-54, (2011) Self-injurious behavior (SIB) is a debilitating characteristic that is prevalent across a broad spectrum of neurodevelopmental disorders. In most of these disorders, some individuals exhibit SIB, whereas others do not. However, the neurobiological mechanisms ... |
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Idiopathic hypersomnia: clinical features and response to treatment.
J. Clin. Sleep Med. 5(6) , 562-8, (2009) A recent American Academy of Sleep Medicine publication identified a need for research regarding idiopathic hypersomnia. We describe various clinical and polysomnographic features of patients with idiopathic hypersomnia, with an emphasis on response to pharma... |
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Methylphenidate use in children and risk of cancer at 18 sites: results of surveillance analyses.
Pharmacoepidemiol. Drug Saf. 16(12) , 1268-72, (2007) A recent report linked methylphenidate (MPH) use in children to cytologic abnormalities in plasma lymphocytes, a possible cancer biomarker. The purpose of this study was to investigate the association of MPH use and childhood cancer risk.Using automated pharm... |
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Self-injurious behavior vs. nonsuicidal self-injury: the CNS stimulant pemoline as a model of self-destructive behavior.
Crisis 33(2) , 106-12, (2012) Historically, the field of self-injury has distinguished between the behaviors exhibited among individuals with a developmental disability (self-injurious behaviors; SIB) and those present within a normative population (nonsuicidal self-injury; NSSI),which ty... |
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Delusional parasitosis and the dopamine transporter. A new insight of etiology?
Med. Hypotheses 68(6) , 1351-8, (2007) Delusional parasitosis (DP) is a psychotic condition in which a person has the unshakeable and mistaken belief (delusion) and/or aberrant perception (hallucination) of being infested with parasites. The disorder will be usually classified in a primary DP-grou... |
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Glutamate-mediated neuroplasticity in an animal model of self-injurious behaviour.
Behav. Brain Res. 189(1) , 32-40, (2008) Self-injurious behaviour (SIB) is exhibited by individuals with a broad variety of developmental disorders and genetic abnormalities, including autism and Lesch-Nyhan, Prader-Willi and Rett syndromes. Most research has focused on environmental factors that re... |