INDINAVIR (100 MG)F0D3080.971MG/MG(AI)
INDINAVIR (100 MG)F0D3080.971MG/MG(AI) structure
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Common Name | INDINAVIR (100 MG)F0D3080.971MG/MG(AI) | ||
|---|---|---|---|---|
| CAS Number | 180683-37-8 | Molecular Weight | 631.80500 | |
| Density | N/A | Boiling Point | 877.9ºC at 760 mmHg | |
| Molecular Formula | C36H49N5O5 | Melting Point | 158 °C | |
| MSDS | N/A | Flash Point | 484.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs.
Biomaterials 37 , 383-94, (2015) With the advent of the Highly Active Antiretroviral Therapy, the morbidity and the mortality associated to HIV have been considerably reduced. However, 35-40 million people bear the infection worldwide. One of the main causes of therapeutic failure is the fre... |
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Blood-brain barrier pharmacoproteomics-based reconstruction of the in vivo brain distribution of P-glycoprotein substrates in cynomolgus monkeys.
J. Pharmacol. Exp. Ther. 350(3) , 578-88, (2014) The aim of this study was to investigate whether in vivo drug distribution in brain in monkeys can be reconstructed by integrating four factors: protein expression levels of P-glycoprotein (P-gp)/multidrug resistance protein 1 at the blood-brain barrier (BBB)... |
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Drug susceptibility to etravirine and darunavir among Human Immunodeficiency Virus Type 1-derived pseudoviruses in treatment-experienced patients with HIV/AIDS in South Korea.
Virol. J. 12(1) , 53, (2015) In South Korea, about 20 types of antiretroviral drugs are used in the treatment of patients with human immunodeficiency virus/acquired immune deficiency syndrome. Since 2010, raltegravir, etravirine, and darunavir have been spotlighted as new drugs for highl... |
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cAMP-dependent insulin modulation of synaptic inhibition in neurons of the dorsal motor nucleus of the vagus is altered in diabetic mice.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(6) , R711-20, (2014) Pathologies in which insulin is dysregulated, including diabetes, can disrupt central vagal circuitry, leading to gastrointestinal and other autonomic dysfunction. Insulin affects whole body metabolism through central mechanisms and is transported into the br... |
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Production of pure indinavir free base nanoparticles by a supercritical anti-solvent (SAS) method.
Drug Dev. Ind. Pharm. 40(12) , 1607-15, (2014) This work investigated the production of pure indinavir free base nanoparticles by a supercritical anti-solvent method to improve the drug dissolution in intestine-like medium.To increase the dissolution of the drug by means of a supercritical fluid processin... |