6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester

6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester Structure
6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester structure
Common Name 6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester
CAS Number 114616-31-8 Molecular Weight 586.54600
Density N/A Boiling Point N/A
Molecular Formula C31H26N2O10 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Defects in calcium homeostasis and mitochondria can be reversed in Pompe disease.

Autophagy 11(2) , 385-402, (2015)

Mitochondria-induced oxidative stress and flawed autophagy are common features of neurodegenerative and lysosomal storage diseases (LSDs). Although defective autophagy is particularly prominent in Pompe disease, mitochondrial function has escaped examination ...

Liver cell uptake and degradation of soluble immunoglobulin G immune complexes in vivo and in vitro in rats.

Hepatology 24 , 169-175, (1996)

Immune complexes were formed between dinitrophenylated human serum albumin (DNP-HSA) and polyclonal rabbit immunoglobulin G (IgG) anti-DNP antibodies at antibody excess. The antigen was labelled with isotope (125I-tyramine-cellobiose) or fluorochrome, (6-[flu...

Dynamics at Lys-553 of the acto-myosin interface in the weakly and strongly bound states.

Biophys. J. 78 , 1441-1448, (2000)

Lys-553 of skeletal muscle myosin subfragment 1 (S1) was specifically labeled with the fluorescent probe FHS (6-[fluorescein-5(and 6)-carboxamido]hexanoic acid succinimidyl ester) and fluorescence quenching experiments were carried out to determine the access...

2,4-Dinitrophenol reduces the reactivity of Lys553 in the lower 50-kDa region of myosin subfragment 1.

Arch. Biochem. Biophys. 505 , 105-111, (2011)

2,4-Dinitrophenol (DNP) increases the affinity of myosin for actin and accelerates its Mg(2+)ATPase activity, suggesting that it acts on a region of the myosin head that transmits conformational changes to actin- and ATP-binding sites. The binding site/s for ...

Avidin binding of carboxyl-substituted biotin and analogues.

Biochemistry 21 , 978-984, (1982)

Production and properties of skeletal myosin subfragment 1 selectively labeled with fluorescein at lysine-553 proximal to the strong actin-binding site.

Biochemistry 34 , 9500-9507, (1995)

We describe, for the first time, the reaction of skeletal myosin subfragment 1 (S-1) with the succinimido ester of 6-[fluorescein-5(and 6)-carboxamido]hexanoic acid (FHS), which takes place at pH 7.0, 20 degrees C, within a 15 min period, in the presence of 1...