Bis(2-methoxyethyl) phthalate
Bis(2-methoxyethyl) phthalate structure
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Common Name | Bis(2-methoxyethyl) phthalate | ||
|---|---|---|---|---|
| CAS Number | 117-82-8 | Molecular Weight | 282.289 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 312.5±22.0 °C at 760 mmHg | |
| Molecular Formula | C14H18O6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 131.6±22.4 °C | |
| Symbol |
GHS08 |
Signal Word | Danger | |
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Determination of Selected Phthalates by Gas Chromatography-Mass Spectrometry in Personal Perfumes.
J. Toxicol. Environ. Health A 78 , 1008-18, (2015) A simple and fast method is proposed to analyze commercial personal perfumes. Our method includes measurement of phthalates, known to be major sources of endocrine disruptor chemicals (EDC), which originate from the less volatile fraction of perfumes. The qua... |
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Teratogenicity of dimethoxyethyl phthalate and its metabolites methoxyethanol and methoxyacetic acid in the rat.
Teratology 32(1) , 25-31, (1985) It is hypothesized that the known teratogen di(2-methoxyethyl) phthalate (DMEP) acts by in vivo hydrolysis to 2-methoxyethanol (2-ME), also a known teratogen, which in turn is metabolized to methoxyacetic acid (MAA), the proximate teratogen. Teratological stu... |
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Evaluation of a testicular sperm head counting technique using rats exposed to dimethoxyethyl phthalate (DMEP), glycerol alpha-monochlorohydrin (GMCH), epichlorohydrin (ECH), formaldehyde (FA), or methyl methanesulphonate (MMS).
Arch. Toxicol. 53(1) , 71-8, (1983) Single dosages of DMEP (1,000-2,000 mg/kg), GMCH (50 mg/kg), ECH (25 and 50 mg/kg), FA (100 and 200 mg/kg), and MMS (100-400 mg/kg) were administered orally to 10 week old male Wistar rats. The rats were necropsied on the 11th day following dosing. The testes... |
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Effects of dimethoxyethyl phthalate, monomethoxyethyl phthalate, 2-methoxyethanol and methoxyacetic acid on post implantation rat embryos in culture.
Toxicol. Lett. 21(1) , 97-102, (1984) The secondary metabolite of dimethoxyethyl phthalate (DMEP), methoxyacetic acid (MAA), but neither the diester nor either of its primary metabolites, monomethoxyethyl phthalate (MMEP) and 2-methoxyethanol (ME), interferes with normal growth and development of... |
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Di(2-ethylhexyl)phthalate induces hepatic tumorigenesis through a peroxisome proliferator-activated receptor alpha-independent pathway.
J. Occup. Health 49(3) , 172-82, (2007) Di(2-ethylhexyl)phthalate (DEHP), a commonly used industrial plasticizer, causes liver tumorigenesis presumably via activation of peroxisome proliferator-activated receptor alpha (PPARalpha). The mechanism of DEHP tumorigenesis has not been fully elucidated, ... |
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Dimethoxyethylphthalate metabolism: teratogenicity of the diester and its metabolites in the pregnant rat.
J. Appl. Toxicol. 4(1) , 35-41, (1984) The rat foetus, in contrast with the maternal liver and placenta, has little or no ability to hydrolyse di-(2-methoxyethyl)-phthalate (DMEP) to mono-2-methoxyethyl)-phthalate (MMEP). At short times after the administration of DMEP to the dam on the 14th day o... |
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Dimethoxyethyl phthalate: embryopathy, teratogenicity, fetal metabolism and the role of zinc in the rat.
Environ. Health Perspect. 45 , 89-97, (1982) A single intraperitoneal injection (0.6 ml/kg) of dimethoxyethyl phthalate (DMEP) was given to groups of Wistar strain rats on day 10, 11, 12, 13 or 14 of gestation. Control rats received 0.6 ml/kg of physiological saline intraperitoneally. In phthalate-treat... |
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Effects of phthalic acid esters on drug metabolizing enzymes of rat liver.
J. Appl. Toxicol. 5(6) , 368-71, (1985) Di(2-ethylhexyl)phthalate (DEHP) inhibited UDP-glucuronyltransferase activity of rat liver in vitro and in vivo. Diethyl phthalate and dimethoxyethyl phthalate also inhibited this enzyme in vitro. On the other hand, DEHP did not inhibit the activity of the cy... |
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Screening-level risk assessment of Di(2-ethylhexyl)phthalate for aquatic organisms using monitoring data in Japan.
Environ. Monit. Assess. 115(1-3) , 451-71, (2006) Screening-level ecological risk assessments of di(2-ethylhexyl)phthalate (DEHP) for aquatic organisms in Japan were conducted using estimated statistical values based on surface water and sediment monitoring data and effect threshold values based on a large a... |