2-phenylindole-3-carboxaldehyde

2-phenylindole-3-carboxaldehyde Structure
2-phenylindole-3-carboxaldehyde structure
Common Name 2-phenylindole-3-carboxaldehyde
CAS Number 25365-71-3 Molecular Weight 221.25400
Density 1.237 g/cm3 Boiling Point 462.9ºC at 760 mmHg
Molecular Formula C15H11NO Melting Point 249-253 °C(lit.)
MSDS Chinese USA Flash Point 237.5ºC
Symbol GHS07
GHS07
Signal Word Warning

Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFκB inhibitors.

Org. Biomol. Chem. 10(44) , 8835-47, (2012)

Development of small molecule drug-like inhibitors blocking both nitric oxide synthase and NFκB could offer a synergistic therapeutic approach in the prevention and treatment of inflammation and cancer. During the course of evaluating the biological potential...

Iridium-catalyzed regio- and enantioselective N-allylation of indoles.

Angew. Chem. Int. Ed. Engl. 48(42) , 7841-4, (2009)

Novel indium-mediated ternary reactions between indole-3-carboxaldehydes-allyl bromide-enamines: facile synthesis of bisindolyl-and indolyl-heterocyclic alkanes. Kumar S, et al.

Tetrahedron Lett. 44(10) , 2101-2104, (2003)

Acylation of indoles by Duff reaction and Vilsmeier-Haack formylation and conformation of N-formylindoles. Chatterjee A and Biswas KM.

J. Org. Chem. 38(23) , 4002-4004, (1973)